Team Grant - Emerging: Novel Alternatives to Antibiotics

CIHR and CIHR's Institute of Infection and Immunity (III) is pleased to announce the results of the "Team Grant - Emerging: Novel Alternatives to Antibiotics" competition.

The specific objectives of the funding opportunity are to:

  • To promote collaboration between researchers working immunology and microbiology to combine their expertise in addressing research questions related to the theme of novel alternatives to antibiotics;
  • To promote collaboration between researchers working in the agriculture sector, on antibiotic resistance and alternatives to antibiotics in food animals, with those researchers working in a clinical environment;
  • To create links between the public and private sector through the promotion of collaborations between the health, agriculture and industry sectors;
  • To encourage the formation of interdisciplinary, multi-sector teams likely to provide novel alternatives to traditional antibiotics with practical applications in both agriculture and health;
  • To foster cross-theme research with an emphasis on a multidisciplinary approach;
  • To create a team environment that favours the development of excellent and innovative research projects that will advance our understanding in the area of alternatives to antibiotics;
  • To train and establish new investigators capable of undertaking research in the area of alternatives to antibiotics.

A total of 27 teams were invited to submit a full application. Applications were reviewed by the Novel Alternatives to Antibiotics (NAA) Peer Review Committee, resulting in the approval of eight (8) applications. (Success rate of 30%)

Name(s)/
Institution Paid/
Title
Partner Total funding Term
DAVIDSON, Alan R
GUTTMAN, David S
MCGAVIN, Martin J
University of Toronto
Genetically Engineered Phage Tail-Like Bacteriocins as an Alternative to Antibiotics
CIHR Institute of Infection and Immunity $1,361,525 5 yr(s)
DENNIS, Jonathan J
University of Alberta
Bacteriophage Therapy Aerosol Delivery and Target Cell Interaction
CIHR Institute of Infection and Immunity $1,240,146 5 yr(s)
HOURY, Walid A
University of Toronto
Towards the Development of a Novel Class of Antibiotics: Activators of Self-Compartmentalizing Proteases
CIHR Institute of Infection and Immunity $1,461,000 5 yr(s)
MOINEAU, Sylvain
Université Laval
Phage therapy for antibiotic-resistant Streptococcus pneumoniae infection
CIHR Institute of Infection and Immunity $1,500,000 5 yr(s)
SAD, Subash
University of Ottawa
Development of novel lipid modulators of innate immunity
CIHR Institute of Infection and Immunity $1,468,250 5 yr(s)
VOGEL, Hans (Harm) J.
University of Calgary
Enhancing innate immunity, antibiotic activity and anti-endotoxin activity with mammalian antimicrobial peptides and proteins: studies of infected mouse models
CIHR Institute of Infection and Immunity $ 1,497,500 5 yr(s)
WEAVER, Donald F
IWK Health Centre (Halifax)
Lipid Membrane Disruptors as adjuncts to antibiotic therapy
CIHR Institute of Infection and Immunity $ 816,000 3 yr(s)
WRIGHT, Gerard D
McMaster University
Antibiotic Adjuvants: Overcoming multi-drug
Resistance in Gram
CIHR Institute of Infection and Immunity $ 1,393,750 5 yr(s)