Randomized Controlled Trials - February-April 2008

* indicates a multicentre study
Principal Investigators Institution/Title Co-investigators Term (years) 1st Year amount Total Amount approved
AARON, Shawn D.
Ottawa Health Research Institute

TNF-alpha Antagonists for Acute Exacerbations of COPD: A Randomized, Double-Blind, Placebo-Controlled Trial*		 Maltais, F., Vandemheen, K.L., Fergusson, D.A., Fitzgerald, J.M., Bourbeau, J.   2 $164,298 $370,675

BHANDARI, Mohit
McMaster University

Guyatt, Gordon H.
McMaster University

Hip Fracture Evaluation with ALternative of Total Hip Arthroplasty Versus Hemi-Arthroplasty (HEALTH): A Multi-centre Randomized Trial Comparing Total Hip Arthroplasty and Hemi-Arthroplasty on Re-operations and Quality of Life in Patients with Femoral Neck Fractures*

 Devereaux, P.J., Walter, S.D., Schmitsch,E.H.,Petrisor, B.A., Heetveld, M.A., Einhorn, T.A., Richardson, M.D., Swiontkowski, M.F., Harris, I., Schwappach, J.R., Coles, C.P., Rosen, C.J., Poolman, R.W., Della Rocca, G.J., Crist, B.D., Van Der Vis, H.M., Goeree, R.A., Tarride, J-E., Adili, A., Koval, K.J., Keating, J.F.,   2 $85,205 $140,721

CHAN, Richard K.
University of Western Ontario

Hachinski, Vladimir, C.
University of Western Ontario

Promoting Adherence to Regimen of Risk Factor Modification by Trained Non-Medical Personnel Evaluated Against Regular Practice Study (PARTNERS)*

 Mayer, C., Majumdar, S.R., McAlister, F.A., Donner, A., Feagan, B.G., Wong, C.J., Harnadek, M., Nolan, R.P.   5 $465,364(includes $12,139 for equipment) $3,641,560

McGRATH, Patrick J.
IWK Health Centre

Cunningham, Charles E.
McMaster University

Delivering treatment for Oppositional Defiant Disorder at a distance: A randomized trial*

 Boyle, M.H., Dooley, M.D., Lipman, E.L., Bagnell, A.L., Brannen, C.L., Corkum, P.V., Stewart, S.H., Reid, G.J., Shannon, H.S.,   4 $375,546(includes $23,629 for equipment) $1,445,704

MOFFET, Hélène
Université Laval

Tousignant, Michel Y.
Université de Sherbrooke

Nadeau, Sylvie
Université de Montreal

Efficacité d'une approche d'intervention à domicile par téléréadaptation suite à une arthroplastie du genou. Un essai clinique multicentrique*

 Corriveau, H., Boissy, P., Merette, C., Marquis, F., Cabana, F., Ranger, P.,   3 $318,405 (includes $47,355 for equipment) $1,011,172

REID, Graham J.
University of Western Ontario

Parenting Matters - Helping Parents with Young Children

 Brown, J.B., Stewart, M.A., Vingilis, E.R.,
Dozois, D.J., Wetmore, S.J., Jordan, J.M., Dickie, G.L., Osmun, W.E., Wade, T.J., Zaric, G.S.,
   1 $60,625(includes $2,586 for equipment) $60,625

STEWART, Duncan J.
St. Michael's Hospital

The eNOS and Cell Therapy - Acute Myocardial Infarction (ENACT-AMI) Trial*

 Kutryk, M.J., Goodman, S.G., Courtman, D.W., Dick, A.J., Parker, T.G., Taljaard, M., Galipeau, J.,   3 $577,613 $1,718,583
The following randomized controlled trial is funded by the CIHR/Rx&D Research Program, in collaboration with AstraZeneca Canada Inc.

BARKUN, Alan
McGill University Health Centre

Implementation of consensus recommendations in the management of Canadian patients with non variceal upper gastrointestinal bleeding: A national cluster randomized trial of a tailored multifaceted intervention*

 Armstrong, D., Dawes, M.G., Donner, A., Enns, R., Martin, J., Moayyedi, P., Romagnuolo, J., Tugwell, P.S.   2 $118,668 $237,336