Canadian Stroke Prevention Intervention Network

Goal

The Canadian Stroke Prevention Intervention Network (C-SPIN) will develop actionable strategies that will make Canada a global leader in clinical stroke research; ensure sustainability of these efforts through strategies to recruit, train, support, and retain clinical scientists; and, in collaboration with other networks, government, and stakeholder groups, implement strategies to reduce the incidence of embolic stroke in Canada by 10% within ten years.

Health burden addressed

Atrial Fibrillation (AF), an abnormal rhythm of the heart, is an ongoing epidemic with a clear relationship to stroke and dementia. AF causes 15% of the 50,000 strokes suffered in Canada each year. The prevalence of AF and the proportion of strokes attributable to AF increases substantially with advancing age and more than 25% of Canadians over age 75 will develop AF, making AF-associated stroke a critical public health issue and a burden for patients and their families.

Approach

C-SPIN brings together a nation-wide multidisciplinary team of cardiologists, neurologists, cardiac surgeons, emergency room physicians, family practitioners, pharmacists, statisticians, methodologists, knowledge translation (KT) experts, and population scientists to pursue a common goal of a major reduction in stroke by means of shared expertise, resources, and harmonized research efforts. C-SPIN will also support the recruitment and retention of the next generation of Canadian clinical researchers in this field. C-SPIN will answer challenging questions that will revolutionize our understanding of AF and stroke, improve healthcare strategies, and reduce the rate of stroke among Canadians.

Key Investigators

Name Role in C-SPIN Main Affiliation
Dr. Jeff Healey PI and Chair of the Canadian Stroke Prevention Intervention Network (C-SPIN) McMaster University and Hamilton Health Sciences
Dr. Stuart Connolly Executive Committee, Theme Leader (Clinical) McMaster University and Hamilton Health Sciences
Dr. Richard Whitlock Theme Leader (Clinical) McMaster University and Hamilton Health Sciences
Dr. Robert Hart Theme Leader (Clinical) McMaster University and Hamilton Health Sciences
Dr. Robby Nieuwlaat Theme Leader (Health Services and Systems) McMaster University and Hamilton Health Sciences
Dr. David Birnie Executive Committee, Theme Leader (Clinical) Ottawa Heart Institute
Dr. Atul Verma Theme Leader (Clinical) Southlake Regional Health Centre
Dr. Russell Quinn Theme Leader (Population and Public Health) Libin Cardiovascular Institute of Alberta
Dr. David Gladstone Theme Leader (Population and Public Health) Sunnybrook Health Science Centre
Dr. Ratika Parkash Theme Leader (Health Services and Systems) Queen Elizabeth II Health Sciences Center
Dr. Denis Roy Theme Leader (Clinical) Montreal Heart Institute
Dr. Paul Dorian Executive Committee St. Michael's Hospital
Dr. Ian Graham Executive Committee Ottawa Hospital Research Institute
Dr. Mike Sharma Executive Committee McMaster University and Hamilton Health Sciences
Dr. Robert Sheldon Executive Committee
Deputy-PI
University of Calgary
Dr. Mario Talajic Executive Committee Montreal Heart Institute
Dr. Anthony Tang Executive Committee University of British Columbia
Dr. Michael Hill Executive Committee Foothills Medical Centre - University of Calgary
Dr. Lisa Dolovitch Executive Committee McMaster University
Dr. Lisa Welikovitch Executive Committee Libin Cardiovascular Institute of Alberta

Funding partners

  • Canadian Institutes of Health Research: $4,350,000
  • Heart & Stroke Foundation: $1,000,000
  • Heart & Stroke Foundation (KT): $211,261
  • Boehringer Ingelheim (Canada) Ltd.: $1,050,000
  • Biotronik Canada Inc.: $660,540
  • University of Ottawa Heart Institute: $400,000
  • Population Health Research Institute: $250,000
  • Medtronic Inc.: $200,000
  • Hamilton Health Sciences Corporation: $193,547
  • Alberta Heart Institute: $150,000
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