Results of the 15/09/2007 200709MOP Operating Grant Competition
Updated : 12/03/2009
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
AGELLON, Luis B $114,088 3 Yr(s) NUT
McGill University
Factors controlling nutrient assimilation
AHERN, Christopher A $131,817 5 Yr(s) CP
University of British Columbia
Investigating anti-arrhythmic inhibition of voltage-gated sodium channels with unnatural amino acids and fluorescence spectroscopy.
ALAIN, Claude ROSS, Bernhard / TREMBLAY, Kelly L
 $85,285 3 Yr(s) BSC
Baycrest Centre for Geriatric Care (Toronto)
Baycrest Hospital (North York)
Neural Mechanisms of Auditory-Based Remediation Programs
ALIBHAI, Shabbir M GUPTA, Vikas $107,500 3 Yr(s) PSD
University Health Network (Toronto)
A comprehensive study of quality of life and fatigue in AML
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
1
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
ALLEN, Upton D GRUNEBAUM, Eyal / MAZZULLI, Tony / READ, Stanley E / ROBINSON, Joan L / TELLIER, Raymond / WEITZMAN, Sheila S / ZIELENSKA, Maria
 $99,742 4 Yr(s) VVP
BEYENE, Joseph
Hospital for Sick Children (Toronto)
Epstein-Barr Virus in Health and Disease in Children and Youth: A Prospective Study of Markers of Virus-Host Interaction and Genetic Variation.
ALMAN, Benjamin A $186,335 5 Yr(s) CIB
Hospital for Sick Children (Toronto)
Molecular mechanisms in Fracture and Wound healing
ALVAREZ, Fernando $111,483 4 Yr(s) GSH
Hôpital Sainte-Justine (Montréal)
Influence of sex organs and hormones on autoimmune hepatitis development
AMRE, Devendra DESLANDRES, Colette / LEVY, Emile / MACK, David R / SEIDMAN, Ernest G
 $140,168 3 Yr(s) PUB
Hôpital Sainte-Justine (Montréal)
Investigation of genetic markers that determine susceptibility and clinical phenotypes of inflammatory bowel diseases
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
2
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
AMREIN, Matthias W SCHURCH, Friedrich S $113,033 5 Yr(s) RS
University of Calgary
Biophysical aspects of the interaction of airborne, ultrafine particles with the peripheral lung: Basic phenomena, health hazards and applications in drug delivery
ANAND-SRIVASTAVA, Madhu B $143,207 5 Yr(s) CSA
Université de Montréal
Natriuretic petpide receptor C (NPR-C), signaling, regulation and cell fucntion
ANIS, Aslam H FISCHER, Benedikt / MACNAB, Ying C / MARSH, David C / NOSYK, Bohdan P / SCHECHTER, Martin T
 $47,850 2 Yr(s) POP
University of British Columbia
An evaluation of long-term medical outcomes following discontinuation of methadone maintenance treatment
ASBRIDGE, Mark CHISHOLM, Douglas / CUSIMANO, Michael D / MAGEE, Kirk D / MANN, Robert E / MURPHY, Nancy / REHM, Juergen T / TALLON, John M
 $218,122 3 Yr(s) BSB
Dalhousie University (Nova Scotia)
Cannabis and traffic collisions: A case crossover study of patients presenting to tertiary care centres in Toronto and Halifax
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
3
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
ASMUNDSON, Gordon J TAYLOR, Steven $81,454 3 Yr(s) PSD
University of Regina (Saskatchewan)
Understanding the co-occurence of PTSD and chronic musculoskeletal pain: Do traumatic experiences alter perception and processing of pain stumuli?
ATTISANO, Liliana $157,381 5 Yr(s) MCC
University of Toronto
Signalling by serine/threonine kinase receptors
AUSTIN, Peter C ANDERSON, Geoffrey M / TU, Jack V
 $49,661 3 Yr(s) HSI
Sunnybrook Health Sciences Centre
Institute for Clinical Evaluative Sciences- Toronto
Statistical methods for health services research
AUSTIN, Richard C $106,022 3 Yr(s) CSC
McMaster University
Role of endoplasmic reticulum (ER) stress in the development and progression of atherothrombotic disease
AUTEXIER, Chantal $121,604 5 Yr(s) BMB
Jewish General Hospital (Montreal)
Telomerase Structure and Function
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
4
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
AVOLI, Massimo $78,685 5 Yr(s) NSA
McGill University
Montreal Neurological Institute
GABAA receptor function and epileptiform hyperexcitability in the fmr1 KO mouse subuculum: an approach to understanding fragile X syndrome
BAI, Donglin $107,143 5 Yr(s) CSA
University of Western Ontario
The role of connexin43 in cardiac function
BAINS, Jaideep S $153,321 5 Yr(s) NSA
University of Calgary
Stress induced plasticity of synaptic inhibition.
BAKER, Glen B TODD, Kathryn G $144,782 5 Yr(s) PS
University of Alberta
Phenylalkylhydrazine drugs and neuroprotection.
BAKOVIC, Marica $110,628 5 Yr(s) M
University of Guelph
Targeted disruption and regulation of the CTP:phosphoethanolamine cytidylyltransferase (Pcyt2) gene
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
5
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
BALDWIN, Troy A $134,677 5 Yr(s) IT
University of Alberta
Molecular examination of thymocyte negative selection in vivo
BALLANYI, Klaus $134,921 5 Yr(s) RS
University of Alberta
Chemosensitivity of the Isolated Inspiratory Center
BALLERMANN, Barbara J LUYCKX, Valerie A $147,911 5 Yr(s) EM
University of Alberta
Glomerular Endothelial Cell Development and Differentiation
BARNETT, Tracie A APPARICIO, Philippe P / DANIEL, Mark / GAUVIN, Lise / GRAY-DONALD, Katherine A / KESTENS, Yan / KOUSHIK, Anita / LAMBERT, Marie / LEFFONDRE, Karen / MCGRATH, Jennifer J
 $82,224 3 Yr(s) POP
Hôpital Sainte-Justine (Montréal)
Investigating the role of the built environment in the development and maintenance of excess weight in a cohort of children at risk for obesity
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
6
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
BAXTER, Nancy N DEL GIUDICE, Lisa M / PASZAT, Lawrence(Larry) F / RABENECK, Linda / SUTRADHAR, Rinku / URBACH, David R
 $118,418 3 Yr(s) POP
St. Michael's Hospital (Toronto)
The Young Adult Survivors of Cancer Study
BEATTIE, Tara L
LEES-MILLER, Susan P $116,745 3 Yr(s) CBT
University of Calgary
Functional Role of hTR/DNA-PK interactions in telomere length maintenace
BEAUCHEMIN, Nicole $177,253 4 Yr(s) CPT
McGill University
CEACAM1 in colon cancer progression
BEHR, Marcel A $118,202 3 Yr(s) MI
The Research Institute of the McGill University Health Centre
NOD2 and mycobacterial infection
BEIER, Frank $123,371 5 Yr(s) DS
University of Western Ontario
Rac1 function in endochondral ossification
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
7
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
BEIER, Frank $121,058 3 Yr(s) CIB
University of Western Ontario
Transforming growth factor alpha in a rodent model of osteoarthritis
BELSHAM, Denise D $158,154 5 Yr(s) M
University of Toronto
Sensing of peripheral nutrient status by the hypothalamus.
BEN AMOR, Leila BARDEN, Nicholas / CHANTAL, Sophie / DESMARAIS, Paul-André / MORASSE, Karine / OUELLET-MORIN, Isabelle
 $100,448 3 Yr(s) BSB
Université Laval
Hôtel-Dieu de Lévis (Lévis, Québec)
Imagerie génétique et Trouble Déficit de l'Attention/Hyperactivité (TDAH) chez les enfants franco-canadiens
BERNARD, Daniel J $140,928 5 Yr(s) E
McGill University
Bone morphogenetic protein signaling in gonadotrope cells
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
8
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
BERNATCHEZ, Pascal N $91,207 3 Yr(s) CSC
University of British Columbia
St. Paul's Hospital, Vancouver
Increased eNOS activity and NO bioavailability through regulated eNOS-Caveolin-1 antagonism: new therapeutic avenues for vascular tone control
BERNSTEIN, Charles N BLANCHARD, James F / GRAFF, Lesley A / LESLIE, William D / LIX, Lisa M / LONGOBARDI, Teresa / VAGIANOS, Kathy / WALKER, John R
 $301,358 5 Yr(s) PUB
University of Manitoba
Understanding the biological, clinical, and psychosocial determinants of health outcomes in inflammatory bowel disease: A research program
BETTS, Dean H MADAN, Pavneesh $111,636 4 Yr(s) BCA
University of Guelph
The role of p66Shc in ROS-mediated cellular senescence
BICHET, Daniel-Georges PETERSON, Alan C $111,980 3 Yr(s) EM
Hôpital du Sacré-Coeur de Montréal
A transgenic approach for the study of the expression and regulation of the human AVPR2 gene
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
9
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
BOGGS, Joan M HARAUZ, George $140,825 5 Yr(s) CP
Hospital for Sick Children (Toronto)
Functions of Myelin Basic Protein in Oligodendrocytes and Myelin
BOHBOT, Véronique RAJAH, Maria N $64,173 2 Yr(s) BCA
Douglas Hospital Research Centre (Verdun, Québec)
Virtual navigation and aging: bringing new perspectives on cognitive function in elderly
BOILEAU, Christelle MARTEL-PELLETIER, Johanne
 $106,410 4 Yr(s) CIB
Centre Hosp. de l'Université de Montréal (CHUM)
Étude de l'expression et de la régulation des récepteurs activés par les protéases (PARs) dans les tissus articulaires et mise en évidence des conséquences physiopathologiques de leur activation
BOIVIN, Guy LIN, Sheng-Xiang $145,426 5 Yr(s) VVP
Université Laval
Antiviral drug resistance in herpesviruses
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
10
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
BORASTON, Alisdair B VOCADLO, David $202,702 5 Yr(s) BMA
University of Victoria (British Columbia)
Degradation of host glycans in the lung by Streptococcus pneumoniae.
BOUCHARD, Jean-Francois $114,480 3 Yr(s) PT
Université de Montréal
Influence of cannabinoids on synaptogenesis and plasticity
BOULIANNE, Gabrielle L $159,628 5 Yr(s) DEV
Hospital for Sick Children (Toronto)
The role of presenilin in Notch signaling
BOYD, Steven K $87,201 4 Yr(s) BME
University of Calgary
Pre-clinical longitudinal assessment of bone health
BREHAUT, Jamie C FERGUSSON, Dean A / KIMMELMAN, Jonathan / SAGINUR, Raphael / SHOJANIA, Kaveh G
 $99,405 3 Yr(s) ELH
Ottawa Health Research Institute
Informing the decision to participate in a clinical trial: Can decision aids improve the quality of trial participation decisions?
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
11
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
BREMNER, Rod $180,050 5 Yr(s) G
University Health Network (Toronto)
Toronto Western Research Institute (Toronto)
A Genome Wide siRNA Screen for Novel IFNgamma signaling components
BROMME, Dieter BRAYER, Gary D / DAVIES, Julian E
 $140,054 3 Yr(s) PS
University of British Columbia
Isolation and characterization of potent and therapeutically relevant cathepsin K and S inhibitors from microbial product libraries
BROOKS-WILSON, Angela R CONNORS, Joseph / GASCOYNE, Randy D / SPINELLI, John Joseph
 $152,409 5 Yr(s) G
University of British Columbia
B.C. Cancer Research Centre (Vancouver)
Population-Based Genetics of Non-Hodgkin Lymphoma
BROPHY, James M DENDUKURI, Nandini / ETMINAN, Mahyar / LEVESQUE, Linda E
 $87,300 2 Yr(s) POP
McGill University
A pharmacoepidemiology study of the cardiovascular safety of bisphosphonates.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
12
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
BROWN, Arthur $156,491 5 Yr(s) CBM
University of Western Ontario
Targeting SOX9 to alter scar gene expression and promote regeneration after spinal cord injury
BROWN, Thomas G DONGIER, Maurice H / LEPAGE, Martin / NADEAU, Louise / NG YING KIN, Ng Mien Kwong / OUIMET, Marie Claude / PRUESSNER, Jens C / TREMBLAY, Jacques
 $86,559 5 Yr(s) GSH
Douglas Hospital Research Centre (Verdun, Québec)
Gender differences in the multidimensional assessment of DWI recidivism risk
BRUNTON, Janet A $83,722 3 Yr(s) NUT
Memorial University of Newfoundland
Dipeptides as trophic factors in the gastrointestinal tract
BURGE, Frederick I ARCHIBALD, Gregory C / CARR, Brendan S / GASS, David A / LAWSON, Beverley J / LUSSING, Frank J / MACPHAIL, Judith H / NATARAJAN, Nandini / PUTNAM, R. W
 $61,069 3 Yr(s) HSI
Dalhousie University (Nova Scotia)
Assessing the feasibility and acceptability of a quality outcome orientation to primary healthcare in Nova Scotia
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
13
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
BURROWS, Lori L $128,155 5 Yr(s) MI
McMaster University
Pseudomonas aeruginosa type IV pilins
CANIGGIA, Isabella POST, Martin / ZAMUDIO, Stacy
 $157,498 5 Yr(s) E
Mount Sinai Hospital (Toronto)
The role of oxygen in regulating placental development
CAO, Xudong GRIFFITH, May C / TSAI, Eve C
 $138,649 3 Yr(s) BME
University of Ottawa
Bioengineering strategies to restore motor function after spinal cord injuries
CARAYANNIOTIS, George $126,786 5 Yr(s) IT
Memorial University of Newfoundland
Immunoregulation of experimental autoimmune thyroiditis
CARBONETTO, Salvatore T RAO, Yong $97,627 3 Yr(s) NSB
The Research Institute of the McGill University Health Centre
Dystroglycan regulates cell polarity and survival in the CNS
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
14
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
CARPENTIER, André C $139,976 3 Yr(s) M
Université de Sherbrooke
Centre hospitalier universitaire de Sherbrooke
Investigation of postprandial fatty acid metabolism in the natural history of type 2 diabetes mellitus (T2DM)
CARPENTIER, Normand C BERNARD, Paul / GRENIER, Amanda M / GUBERMAN, Nancy / KERGOAT, Marie-Jeanne
 $60,000 3 Yr(s) SDA
Institut universitaire de gériatrie de Montréal
Using the Life Course Perspective to plan interventions among families of people with Alzheimer's disease
CARTER, Jacqueline C
CROSBY, Ross / OLMSTED, Marion P / WOODSIDE, D. B
 $46,441 3 Yr(s) PSD
University Health Network (Toronto)
A longitudinal study of relapse and recovery in anorexia nervosa
CEDDIA, Rolando $113,534 3 Yr(s) M
York University (Toronto, Ontario)
Regulation of white adipose tissue metabolism by AMPK
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
15
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
CHAHINE, Mohamed $129,325 5 Yr(s) CP
Université Laval
Centre de recherche Université Laval-Robert- Giffard (QC)
Modulation of Nav1.7 and Nav1.8 peripheral nerve Na channels by Kinases, local anaesthetics and auxiliary beta-subunits
CHAN, Peter T HALES, Barbara F / ROBAIRE, Bernard
 $114,639 4 Yr(s) CIA
McGill University
Impact of cancer and chemotherapy on the nuclear proteins in spermatozoa.
CHAUDHURI, Avi $130,580 5 Yr(s) BSC
McGill University
The development of complex vision in primates
CHEN, Hsiao-Huei $123,063 5 Yr(s) NSB
Ottawa Health Research Institute
Control of sensory neuron development
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
16
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
CHEN, Robert DASKALAKIS, Zafiris J / KENNEDY, James L / WONG, Albert H
 $184,040 5 Yr(s) MOV
University Health Network (Toronto)
Toronto Western Research Institute (Toronto)
Mechanisms of cortical inhibition, facilitation and plasticity in humans
CHEN, Xi-Kuan KREWSKI, Daniel R / SMITH, Graeme N / WALKER, Mark C / WEN, Shi Wu / YANG, Qiuying
 $45,905 2 Yr(s) CHI
University of Ottawa
Beta blockers for the treatment of chronic hypertension and gestational hypertension and adverse perinatal outcomes
CHENG, Hai-Ying M $91,409 5 Yr(s) BSA
University of Ottawa
Signal Transduction Mechanisms Underlying Circadian Timekeeping in Mammals
CHEUNG, Po-Yin $160,605 4 Yr(s) CSB
University of Alberta
The cardiovascular support in newborns with hypoxia-reoxygenation injury
CHOY, Wing-Yiu $127,882 5 Yr(s) BMA
University of Western Ontario
Structural studies of intrinsically disordered proteins
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
17
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
CLARKE, David M $102,175 3 Yr(s) CBM
University of Toronto
The Molecular Mechanism of Rescue of CFTR Folding Defects Using Pharmacological Chaperones.
COLAVITA, Antonio $138,807 3 Yr(s) DEV
Ottawa Health Research Institute
Understanding the Role of Planar Cell Polarity Proteins in Establishing and/or Maintaining Neuronal Polarity in C. elegans
COLES, John G $102,417 4 Yr(s) CSB
Hospital for Sick Children (Toronto)
Role of integrin-linked kinase (ILK) in Tetralogy of Fallot
COLLINS, Richard A
$148,288 5 Yr(s) BMB
University of Toronto
Mechanism of catalysis and biological significance of the Neurospora VS ribozyme
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
18
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
CORNELL, Rosemary B $127,645 5 Yr(s) BMA
Simon Fraser University (Burnaby, B.C.)
Cytidylyltransferase - membrane interactions: Reciprocal effects on the protein and the membrane
COTE, Jocelyn $152,427 5 Yr(s) CBM
University of Ottawa
The role of the tudor domain in SMN axonal activities
COULTON, James W $160,497 5 Yr(s) BMA
McGill University
Structural biology of the bacterial TonB interactome
COUTURE, Patrick LAMARCHE, Benoît / VOHL, Marie-Claude
 $94,650 3 Yr(s) NUT
Université Laval
Effects of n-3 polyunsaturated fatty acids on chylomicron secretion and expression of genes that regulate intestinal lipid metabolism in men with type 2 diabetes
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
19
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
COWEN, Leah E $109,263 5 Yr(s) MI
University of Toronto
Role of the Molecular Chaperone Hsp90 in Fungal Evolution, Drug Resistance, and Infectious Disease
CROSS, James C $202,349 5 Yr(s) DEV
University of Calgary
Regulation of chorioallantoic morphogenesis
CSIZMADI, Ilona BRYANT, Heather E / FRIEDENREICH, Christine M / JONES, Peter J / KOPCIUK, Karen A / LAU, David C / YASUI, Yutaka
 $95,268 2 Yr(s)
6 Mths
 PUB
ROBSON, Paula J
Alberta Cancer Board (Edmonton)
Alberta Cancer Board (Calgary)
Development of a multidimensional measure of activity energy expenditure for use in large populations.
DANIEL, Sam J $99,491 3 Yr(s) CIA
The Research Institute of the McGill University Health Centre
Montreal Children's Hospital
Prevention of cisplatinum ototoxicity
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
20
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
DAVIS, Elaine C $114,306 3 Yr(s) CSC
McGill University
Regulation of Vascular Wall Development
DAY, Robert NEUGEBAUER, Witold A $134,550 3 Yr(s) E
Université de Sherbrooke
PACE4 and prostate cancer
DELANEY, Kerry R $129,829 5 Yr(s) NSB
University of Victoria (British Columbia)
Cellular and Network Analysis of Olfactory Bulb
DENAULT, Jean-Bernard $110,888 5 Yr(s) BMA
Université de Sherbrooke
Mécanismes d'activation des caspases apoptotiques
DENNIS, James W $129,000 5 Yr(s) MCC
Mount Sinai Hospital (Toronto)
A systems approach to metabolic regulation of cancer growth
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
21
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
DESNOYERS, Serge BAZIN, Richard / GUERIN, Sylvain L
 $108,895 3 Yr(s) CIA
Université Laval
Centre hospitalier de l'Université Laval (Québec)
Expression of the human PARP-1/PARG genes and poly(ADP-ribose) metabolism in diabetic retinopathy
DEWEY, Deborah M BARLOW, Karen M / BEAULIEU, Christian / BERNIER, Francois P / CANTELL, Marja C / CAUSGROVE DUNN, Janice L / GOODYEAR, Bradley G / KOOISTRA, Libbe / MARAJ, Brian K / MOHAMED, Ismail S / WELSH, Timothy N
 $227,173 5 Yr(s) CHI
University of Calgary
Developmental Motor Disorders: From Genes to Behaviour
DIMITROULAKOS, Jim $121,949 3 Yr(s) CBT
Ottawa Health Research Institute
Evaluating statins and receptor tyrosine kinase inhibitors as a novel combinational anti-cancer therapeutic approach
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
22
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
DIONNE, Isabelle AUBERTIN, Mylene / BROCHU, Martin / KHALIL, Abdelouahed
 $141,338 3 Yr(s) NUT
Université de Sherbrooke
Centre de recherche sur le vieillissement (QC)
Aerobic exercise and phytoestrogens: a synergistic effect on factors predisposing to CVD in postmenopausal women
DIRKS, Peter B $101,166 5 Yr(s) MCC
Hospital for Sick Children (Toronto)
Asymmetrical self renewal in normal and cancer stem cells of the human brain
DOSTIE, Josée $151,751 5 Yr(s) GMX
McGill University
Role of Spatial Chromatin Organization in Genome Regulation
DOYON, Julien BENALI, Habib / BOULANGER, Yvan / HOGE, Richard D / LEHERICY, Stéphane / MAQUET, Pierre A / PEIGNEUX, Philippe
 $109,654 5 Yr(s) BSC
Institut universitaire de gériatrie de Montréal
Université de Montréal
Physiological mechanisms associated with the creation, consolidation and reconsolidation of a motor memory trace examined through functional brain imaging
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
23
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
DREW, Trevor B STAPLEY, Paul J $188,371 5 Yr(s) MOV
Université de Montréal
Brainstem control of movement and posture in the cat
DROUIN, Jacques BALSALOBRE, Aurelio / VALLETTE-KASIC, Sophie
 $174,008 5 Yr(s) E
Institut de recherches cliniques de Montréal
Regulatory mechanisms for differentiation of pituitary POMC cells
DUBOIS, Claire M $122,015 4 Yr(s) CBM
Université de Sherbrooke
Characterization of tumor-like invadopodia in arthritic synovial cells
DUBOIS, Lise POTVIN KENT, Monique C $82,706 3 Yr(s) NUT
University of Ottawa
Television food advertising, obesity and food intake in anglophone and francophone children in Ontario and Quebec
DUCHAINE, Thomas $125,323 5 Yr(s) GMX
McGill University
RNAi-mediated genetic regulation loops
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
24
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
DUMONT, Serge BURGE, Frederick I / CHOCHINOV, Harvey M / JOHNSTON, Grace M
 $97,370 3 Yr(s) HPM
JACOBS, Philip
VILLENEUVE, Patrick
Université Laval
Centre hospitalier de l'Université Laval (Québec)
Palliative care in Canada II: The economic perspective in rural areas
DUNN, James R HWANG, Stephen W / JANUS, Magdelena / MATHESON, Flora I / MOINEDDIN, Rahim / MUNTANER, Carles / O'CAMPO, Patricia
 $223,959 5 Yr(s) POP
St. Michael's Hospital (Toronto)
Effects of social housing on adult and child mental health: A prospective study in the GTA west
DUONG, Frank $126,143 5 Yr(s) BMA
University of British Columbia
Molecular dynamics of protein translocation through the bacterial membrane
DURHAM, Heather D GENTIL, Benoit J / HANCOCK, Mark A
 $131,010 4 Yr(s) NSA
McGill University
The Role of Protein Chaperones in Regulating Neurofilament Dynamics in Peripheral Sensorimotor Neuropathies
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
25
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
EAVES, Connie J $142,609 3 Yr(s) DEV
University of British Columbia
B.C. Cancer Research Centre (Vancouver)
Characterization of Human Mammary Epithelial Stem Cells.
ELLEN, Richard P $144,183 5 Yr(s) DS
University of Toronto
Signaling pathways for actin and chemotaxis perturbation in neutrophils by Treponema denticola
ELLIOTT, Charlene D $44,947 3 Yr(s) NUT
University of Calgary
Food marketing and childhood obesity: Assessing child and parental responses to 'fun foods'
ELLIOTT, Janet A THOMPSON, Richard B $90,579 4 Yr(s) BME
MCGANN, Locksley E
University of Alberta
Thermodynamics in Cryobiology and Applications in Biopreservation
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
26
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
EPAND, Richard M $82,044 5 Yr(s) MI
McMaster University
Microbial Membranes and the Action of Antimicrobial Agents
EVANS, Alan C $148,178 5 Yr(s) BSC
McGill University
3-D Morphometry of Human Cortex
EZZAT, Shereen Z ASA, Sylvia L $140,567 5 Yr(s) CPT
University Health Network (Toronto)
Fibroblast Growth Factor Receptor 2 In Normal and Cancer Cells
FEHLINGS, Darcy L GOLDSMITH, Charles H / NARAYANAN, Unni / ROSENBAUM, Peter L / WRIGHT, Virginia F
 $94,657 4 Yr(s)
6 Mths
 CHI
Bloorview Kids Rehab (Toronto)
An Evaluation of the Long-term Effectiveness of Botulinum Toxin in Children with Spastic Cerebral Palsy
FELDMAN, Howard HALLAM, Bradley J / HSIUNG, Ging-Yuek R / JACOVA, Claudia / RABHERU, Kiran / RUTH, Thomas J / STOESSL, A. Jonathan
 $317,108 5 Yr(s) BCA
MACKENZIE, Ian R
University of British Columbia
Frontotemporal Lobar Degeneration with Ubiquitinated Inclusions: Genetic, Clinical, Pathological and Biomarker Studies
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
27
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
FENSTER, Aaron CHIN, Joseph L / IZAWA, Jonathan I / MCKENZIE, Charles A
 $122,366 5 Yr(s) MPI
Robarts Research Institute - U.W.O. (London, Ont.)
University of Western Ontario
3D transrectal ultrasound-guided prostate biopsy
FERGUSON, Stephen S $151,103 4 Yr(s) PT
University of Western Ontario
Regulation of CRF1/5HT2 Receptor Signalling Complexes
FERNANDES, Karl J $98,343 3 Yr(s) BCA
Université de Montréal
Neural precursors during aging and Alzheimer's Disease
FLORAS, John S BRADLEY, Douglas T / KIMMERLY, Derek S
 $60,000 3 Yr(s) CSB
University Health Network (Toronto)
Central Regulation of Autonomic Cardiovascular Function in Human Heart Failure and Obstructive Sleep Apnea
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
28
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
FORTIN, Sylvie ALVAREZ, Fernando / BIBEAU, Gilles / CARNEVALE, Franco (Frank) A / DUVAL, Michel / GAUVIN, France
 $130,057 3 Yr(s) ELH
Hôpital Sainte-Justine (Montréal)
Pratiques cliniques hospitalières et pluralisme urbain: L'arrimage d'une pédiatrie à la diversité de son milieu, PHASE II.
FOURNIER, Alain $101,273 5 Yr(s) PT
INRS - (Québec, QC)
Molecular pharmacology of urotensin II, a cardiovascular peptide hormone.
FOWKE, Keith R $110,682 3 Yr(s) VVP
University of Manitoba
Assessment of the functional mechanisms driving immune quiescence and infection resilience observed in HIV resistant sex workers.
FRADET, Yves BERGERON, Alain / DE CAMPOS LIMA, Pedro O / LACOMBE, Louis / LARUE, Hélène
 $127,021 3 Yr(s) CBT
Université Laval
Centre de recherche de L'Hôtel-Dieu de Québec
Cancer testis antigen-based immunotherapy of bladder cancer
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
29
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
FRADIN, Cecile $122,550 5 Yr(s) BMA
McMaster University
The structural basis for Bax-induced membrane permeabilization during apoptosis
FRANK, Cyril B HART, David A / RONSKY, Janet L / SHRIVE, Nigel G
 $135,751 5 Yr(s) BME
University of Calgary
Ligament Transplantation
FRANKLAND, Paul W $130,161 5 Yr(s) BSA
Hospital for Sick Children (Toronto)
Adult neurogenesis and hippocampal memory formation
FUNNELL, Barbara E $143,758 5 Yr(s) BMB
University of Toronto
Mechanisms of action of ParA and ParB proteins in bacterial plasmid segregation
GAGLIARDI, Anna R BROUWERS, Melissa C / GRIMSHAW, Jeremy M / LEMIEUX-CHARLES, Louise / MCLEOD, Robin S / PALDA, Valerie A
 $67,838 2 Yr(s) KTE
Sunnybrook Health Sciences Centre
Developing capacity for knowledge translation: Identifying factors that improve practice guideline implementation
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
30
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
GAGNON, France WELLS, Philip S $138,275 4 Yr(s) G
University of Toronto
Search for modifier genes in familial thrombophilia with Factor V Leiden variant: A look at the hemostatic pathways
GAISANO, Herbert Y $114,294 5 Yr(s) M
University of Toronto
Rescuing insulin exocytotic defects in type 2 diabetes
GASCOYNE, Randy D CONNORS, Joseph / STEIDL, Christian
 $130,317 3 Yr(s) CBT
University of British Columbia
BC Cancer Agency (Vancouver, BC)
Predicting treatment response in Hodgkin Lymphoma by identifying new molecular markers
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
31
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
GAUDET, Daniel ABRAHAMOWICZ, Michal M / LABERGE, Luc / LEONARD, Gabriel / PAUSOVA, Zdenka V / PERRON, Michel / PIKE, G. Bruce / RICHER, Louis / SEGUIN, Jean R
 $272,095 5 Yr(s) CHI
PAUS, Tomas
Université de Montréal
Hôpital de Chicoutimi (Québec)
Long-term consequences of prenatal exposure to maternal cigarette smoking on brain structure, function and mental health in adolescence: role of genes and environment in brain development
GEORGE, Susan R
$140,567 5 Yr(s) BSA
O'DOWD, Brian F
University of Toronto
Regulation of GPCR signaling complexes mediating opioid action
GHAHARY, Aziz ONG, Christopher J / ULUDAG, Hasan
 $157,422 5 Yr(s) CIB
University of British Columbia
Development and Application of Non- Rejectable Allogenic Skin Substitute as a Wound Coverage
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
32
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
GIANGREGORIO, Lora Marie ADACHI, Jonathan D / MCCARTNEY, Neil / PAPAIOANNOU, Alexandra / POPOVIC, Milos R / THABANE, Lehana
 $85,477 3 Yr(s)
6 Mths
 PUB
University of Waterloo (Ontario)
McMaster University
Bone quality in individuals with chronic spinal cord injury
GLAZIER, Richard H BARNSLEY, Janet / GUTTMANN, Astrid / HOGG, William E / JAAKKIMAINEN, Ritva L / MANUEL, Douglas G / RHODES, Anne E / SCHULL, Michael J / STEELE, Leah S / STEWART, Moira A / STUKEL, Therese A / THIND, Amardeep / TU, Karen / UPSHUR, Ross E / ZWARENSTEIN, Merrick F
 $179,181 4 Yr(s) HSI
St. Michael's Hospital (Toronto)
Institute for Clinical Evaluative Sciences- Toronto
Examining the impact of primary care reform in Ontario on access to and quality of care
GLOVER, John R $122,310 3 Yr(s) CP
University of Toronto
Structure, function, and biology of the chaperone Hsp104
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
33
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
GOLTZMAN, David $139,860 4 Yr(s) CIB
McGill University
Hormonal regulation of skeletal and mineral homeostasis
GORDON, John R $134,934 5 Yr(s) IT
University of Saskatchewan
Mechanisms mediating the therapeutic effects of tolerogenic dendritic cells
GORNITSKY, Mervyn DAGENAIS, Marie / HUDSON, Marie / STEELE, Russell J
 $114,387 2 Yr(s) DS
BARON, Murray
Jewish General Hospital (Montreal)
The impact of orofacial manifestations of systemic sclerosis on health-related quality of life
GOSGNACH, Simon $100,057 3 Yr(s) MOV
University of Alberta
Analysis of the role of genetically-defined interneurons in the operation of the locomotor CPG.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
34
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
GOSSELIN, Jean $115,909 3 Yr(s) PT
Université Laval
Centre Hospitalier Universitaire de Québec
Characterization of the physiological action of leukotriene B4 on the innate defense against viral infection
GOTMAN, Jean DUBEAU, François / PIKE, G. Bruce
 $152,350 5 Yr(s) MPI
McGill University
Montreal Neurological Institute
Electrical and metabolic analysis of human epileptogenic lesions
GRACE, Sherry L ARTHUR, Heather M / PRIOR, Peter L / REID, Robert D / STEWART, Donna E / SUSKIN, Neville G
 $92,041 3 Yr(s) HSR
University Health Network (Toronto)
Comparing paper versus electronic transmission of cardiac rehabilitation summaries to primary care physicians: A multi-site multi-method study of information flow and content
GRATTON, Jean-Philippe $103,476 5 Yr(s) MCC
Institut de recherches cliniques de Montréal
Molecular basis of tumor vessels hyperpermeability
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
35
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
GRAY, Douglas A $82,001 3 Yr(s) BCA
Ottawa Health Research Institute
Refinement of a computer model of protein degradation and aging using a well characterized molecular circuit
GREEN, Robin E BAYLEY, Mark T / CHRISTENSEN, Bruce K / HEBERT, Deborah A / INNESS, Elizabeth L / MCILROY, William E / MONETTE, Georges
 $129,410 3 Yr(s) BSB
MIKULIS, David J
Toronto Rehab Institute
Cognitive and Motor recovery following traumatic brain injury: Investigations of novel mechanisms and outcome predictors - Phase 2
GREWAL, Savraj S $137,558 5 Yr(s) CBM
University of Calgary
The control of ribosome synthesis and cell growth by the target-of-rapamycin (TOR) pathway
GROSS, Gil J REDINGTON, Andrew N $132,295 4 Yr(s) CSB
Hospital for Sick Children (Toronto)
Contractile adaptations to constrained heart rate conditions
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
36
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
GRUNAU, Ruth E BRANT, Rollin F / MILLER, Steven P / SYNNES, Anne R / WEINBERG, Joanne / WHITFIELD, Michael F
 $124,757 5 Yr(s) CHI
University of British Columbia
Child and Family Research Institute
Stress and neurodevelopment in children born preterm
GUILLEMETTE, Gaétan $122,223 5 Yr(s) PT
Université de Sherbrooke
Régulation des récepteurs de l'inositol 1,4,5- trisphosphate par FKBP12 via ses effecteurs mTOR et calcineurine
HADDAD, Elie LE DEIST, Francoise L / PSHEZHETSKY, Alexey V
 $97,564 3 Yr(s) EM
Hôpital Sainte-Justine (Montréal)
Study of the mechanisms of idiopathic nephrotic syndrome by using a new mouse model of the disease obtained by humanizing NOD/SCID mice with patients' CD34+ cells.
HAERYFAR, S.M. Mansour $126,013 5 Yr(s) IT
University of Western Ontario
Regulation of antiviral cytotoxic T lymphocyte responses by innate invariant natural killer T cells
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
37
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
HALES, Barbara F $160,340 5 Yr(s) PT
McGill University
Teratogen-induced signalling pathways during limb development
HALLAM, Steven J $132,999 3 Yr(s) GMX
University of British Columbia
Functional Metagenomic Investigation of Archaeal Serine Protease Inhibitors
HANCOCK, Robert Ernest W HAMILL, Pamela C $109,107 5 Yr(s) MI
University of British Columbia
Design and Function of Antimicrobial Peptides
HANLY, John G CLARKE, Ann E / FAREWELL, Vernon T / FORTIN, Paul R / GLADMAN, Dafna D / UROWITZ, Murray B
 $162,734 5 Yr(s) CIB
Dalhousie University (Nova Scotia)
An international, multi-center, prospective, inception cohort study of neuropsychiatric systemic lupus erythematosus (NP-SLE)
HARDER, Kenneth W $136,164 5 Yr(s) IT
University of British Columbia
Signaling thresholds controlling dendritic cell, monocyte, macrophage development and the innate immune response
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
38
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
HARDY, Pierre $138,717 3 Yr(s) CIA
Hôpital Sainte-Justine (Montréal)
Anti-Angiogenic Properties of Lymphocyte Microparticles: Innate Recognition and Regulation by Phosphatidylserine Receptor in Oxygen-Induced Retinopathy.
HAYDEN, Elizabeth P CHEN, Xinyin / HILL, Kathleen A / SINGH, Shiva M
 $156,874 5 Yr(s) BSB
University of Western Ontario
Gene-environment interplay and the developmental psychopathology of internalizing disorders
HAYNES, Robert B MCKIBBON, Kathleen Ann $130,185 3 Yr(s) KTE
McMaster University
Clinical search retrieval and dissemination from large internet databases such as MEDLINE
HEMMELGARN, Brenda R AHMED, Sofia B / CROWSHOE, Lynden (Lindsay / FARIS, Peter D / GHALI, William A / MANNS, Braden J / TONELLI, Marcello A
 $79,421 2 Yr(s) ABH
University of Calgary
Progression and management of chronic kidney disease among First Nations People
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
39
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
HEMMINGS, Denise G $106,395 3 Yr(s) CIA
University of Alberta
Regulation of uterine and placental vascular responses to sphingosine 1-phosphate
HENDY, Geoffrey N $140,964 5 Yr(s) M
The Research Institute of the McGill University Health Centre
McGill University
Extracellular calcium-sensing receptor: studies of gene expression and regulation
HERZOG, Walter $102,183 3 Yr(s) MOV
University of Calgary
Mechanical properties of sarcomeres and mechanisms of contraction
HESS, David A $118,016 3 Yr(s) CSC
Robarts Research Institute - U.W.O. (London, Ont.)
University of Western Ontario
Cellular constituents and paracrine pathways that mediate functional vascular regeneration.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
40
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
HESS, David A $110,139 4 Yr(s) E
University of Western Ontario
Formation of a regenerative niche for the endogenous recovery of beta-cell function.
HISCOTT, John $176,816 5 Yr(s) VVP
LIN, Rongtuan
Jewish General Hospital (Montreal)
Molecular Interactions regulating RIG-I signaling to the Innate Antiviral Response
HO, Anthony K $158,781 5 Yr(s) E
University of Alberta
The role of histone modifications in adrenergic- stimulated gene expression in the rat pineal gland
HOBMAN, Tom C $126,039 5 Yr(s) VVP
University of Alberta
Analyses of togavirus capsid protein functions in virus replication
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
41
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
HOLLOWAY, Alison C GERSTEIN, Hertzel C / MORRISON, Katherine Mary / TARNOPOLSKY, Mark A
 $103,873 5 Yr(s) CIA
McMaster University
In utero exposure to nicotine and postnatal health consequences: Mechanisms of dysglycemia
HOLROYD, Clay B KERNS, Kimberly A / MUELLER, Ulrich
 $73,000 5 Yr(s) BSB
University of Victoria (British Columbia)
Neural mechanisms of reward learning and cognitive control in children with ADHD
HUI, Chi-Chung $144,862 4 Yr(s) DEV
Hospital for Sick Children (Toronto)
Control of hindlimb development and patterning by the Iroquois homeobox genes
HWANG, Stephen W DUNN, James R / HOCH, Jeffrey S / HUBLEY, Anita M / HULCHANSKI, J. D / KLODAWSKY, Fran / NISENBAUM, Rosane
 $400,618 4 Yr(s) POP
AUBRY, Tim D
FARRELL, Susan J
PALEPU, Anita
St. Michael's Hospital (Toronto)
The Health and Housing in Transition (HHiT) Study: A Longitudinal Study of the Health of Homeless and Vulnerably Housed Adults in Vancouver, Toronto, and Ottawa
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
42
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
IGDOURA, Suleiman A $148,254 5 Yr(s) G
McMaster University
Molecular mechanisms of pathogenesis for lysosomal storage diseases
JEANNOTTE, Lucie AUBIN, Josée $194,317 5 Yr(s) DEV
Université Laval
Centre de recherche de L'Hôtel-Dieu de Québec
Analysis of Hoxa5 gene function in cell fate during mammalian organogenesis
JEFFERIES, Wilfred A $141,771 5 Yr(s) IT
University of British Columbia
Studies on Antigen Presentation in Dendritic Cells
JOHNSON, James D $119,985 3 Yr(s) M
University of British Columbia
Intracellular calcium stores as master regulators of pancreatic beta-cell survival: Studies on transplantable human islets and knockout mice
JOHNSRUDE, Ingrid S $95,853 5 Yr(s) BSC
Queen's University (Kingston, Ontario)
From sound to meaning: The neural and functional bases of speech perception.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
43
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
JONES, Nicola L $103,575 5 Yr(s) EM
Hospital for Sick Children (Toronto)
Role of autophagy during H. pylori infection and disease
JOSEPH, Jamie W $85,512 3 Yr(s) M
University of Waterloo (Ontario)
Novel pathways in the metabolic regulation of insulin release from pancreatic beta-cells.
JOSSELYN, Sheena A $132,195 5 Yr(s) BSA
Hospital for Sick Children (Toronto)
The role of the transcription factor CREB in mammalian memory
KANDEL, Rita A MASSICOTTE, Eric M / SANTERRE, Paul
 $152,179 3 Yr(s) BME
Mount Sinai Hospital (Toronto)
Study of annulus fibrosus cells on polyurethane scaffolds and the regulation of matrix orientation: Towards tissue engineering a functional intervertebral disc
KAPUS, Andras $123,564 5 Yr(s) CBM
St. Michael's Hospital (Toronto)
Myocardin-related transcription factor: a central regulator of epithelial-myofibroblast transition
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
44
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
KARMAZYN, Morris $159,014 5 Yr(s) CSA
University of Western Ontario
Role of Leptin in Cardiac Hypertrophy and Heart Failure
KAVANAGH, Brian Patrick W POST, Martin $138,454 5 Yr(s) RS
Hospital for Sick Children (Toronto)
Ventilator-Induced Lung Injury: Linking Gene Expression, Physiology and Outcome
KAY, Robert J CORNELL, Rosemary B $114,047 3 Yr(s) CBM
University of British Columbia
B.C. Cancer Research Centre (Vancouver)
Membrane-specific targeting of RasGRPs: Mechanisms and consequences
KEIGHTLEY, Michelle JOHNSTON, Karen M / LOBAUGH, Nancy J / PTITO, Alain
 $111,970 3 Yr(s) CHI
University of Toronto
An fMRI Study of the Neural and Clinical Implications of Pediatric Sports-Related Concussion
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
45
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
KELEMEN, Linda E BROOKS-WILSON, Angela R / COOK, Linda S / LE, Nhu D
 $161,319 3 Yr(s) POP
Alberta Cancer Board (Edmonton)
Alberta Cancer Board (Calgary)
Genetic variation in the one carbon transfer pathway and ovarian cancer risk: a replication- association study
KELLY SPURLES, Patricia L DOYLE, Judith E $81,356 1 Yr(s) CHI
Mount Allison University (New Brunswick)
Breastfeeding decisionmaking in low-initiation rate populations: A qualitative study of women's experience and decisionmaking regarding breastfeeding supplementation and cessation in New Brunswick and Nova Scotia
KIBAR, Zoha $125,343 5 Yr(s) G
Hôpital Sainte-Justine (Montréal)
Identification and characterization of genes predisposing to Neural Tube Defects in humans
KIDDER, Gerald M $158,215 5 Yr(s) DEV
University of Western Ontario
Roles of gap junctional coupling in oogenesis
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
46
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
KIM, Peter C $129,363 4 Yr(s) BCA
Hospital for Sick Children (Toronto)
Models and Mechanisms of Accelerated Ageing: P63 Regulation of Progenitor Cells and Cellular Senescence in Intestine
KIRBY, Gordon M $88,758 3 Yr(s) PS
University of Guelph
Role of glutathione transferases in stress cell signaling
KNAUS, Edward E $148,609 3 Yr(s) PS
University of Alberta
The design and evaluation of non-ulcerogenic COX-2 and/or 5-LOX antiarthritic agents and nitric oxide donor prodrug derivatives thereof.
KOEBERLE, Paulo D
$85,739 3 Yr(s) CIA
University of Toronto
The Role of Extracellular Matrix Interactions in Adult CNS Neuroprotection
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
47
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
KOEHOORN, Mieke W BARER, Morris L / CHHOKAR, Rahul S / COTE, Pierre / HOGG- JOHNSON, Sheilah / MCGRAIL, Kimberlyn M / MCLEOD, Christopher B
 $113,088 3 Yr(s) HSI
University of British Columbia
Musculoskeletal surgeries among injured workers: Investigation of outcomes by surgical setting and expedited status
KONTOS, Pia C COLANTONIO, Angela / COTT, Cheryl A / GILBERT, Julie E / KEIGHTLEY, Michelle / MITCHELL, Gail J
 $115,200 3 Yr(s) KTE
Toronto Rehab Institute
After the Crash: Exploring knowledge translation through research-based drama
KORNELUK, Robert G $170,662 3 Yr(s) MCC
Children's Hospital of Eastern Ontario (Ottawa)
The role of the Inhibitors of Apoptosis (IAPs) in cancer
KOSZYCKI, Diana BRADWEJN, Jacques / FLAMENT, Martine F / GOW, Robert M / KENNEDY, James L / MERALI, Zulfiquar / SCHNEIDER, Barry H / TALJAARD, Monica
 $128,403 5 Yr(s) CHI
University of Ottawa
University of Ottawa Institute of Mental Health Research
Children at risk for panic disorder
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
48
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
KOTHARY, Rashmi K $146,114 5 Yr(s) CBM
Ottawa Health Research Institute
Understanding the pathophysiology of spinal muscular atrophy
KRAUSE, Henry M $258,000 5 Yr(s) GMX
University of Toronto
Genome-wide analysis of mRNA subcellular trafficking
LABELLE, Hubert B BEAUSEJOUR, Marie / FELDMAN, Debbie / FORTIER, Isabel / GOULET, Francois / GOULET, Lise / GRIMARD, Guy / PARENT, Stefan / ROSSIGNOL, Michel
 $74,937 3 Yr(s) HSR
Hôpital Sainte-Justine (Montréal)
Plan d'organisation des services pour la prise en charge appropriée des patients avec scoliose suspectée.
LACHAPELLE, Pierre SAPIEHA, Przemyslaw S / VARMA, Daya R
 $112,240 4 Yr(s) CIA
CHEMTOB, Sylvain
The Research Institute of the McGill University Health Centre
Retinal distribution of structural and functional changes in retinopathy of prematurity: Involvement of choroid affected by nitrative stress mediators.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
49
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
LAI, Daniel W ANDRUSKE, Cynthia L / CHAN, Sing Mei / DONNELLY, Tam T / SUROOD, Shireen
 $73,708 3 Yr(s) SDA
O'CONNOR, Deborah
University of Calgary
Multicultural perspectives of family caregiving for the aging population
LAM, Tony K $119,335 5 Yr(s) M
University Health Network (Toronto)
CNS Nutrient Sensing, Food Intake and Glucose Homeostasis
LAM, Wan L LAM, Stephen / MACAULAY, Calum E / NG, Raymond
 $171,057 4 Yr(s) GMX
University of British Columbia
B.C. Cancer Research Centre (Vancouver)
Integrative analysis of lung cancer genomes
LAMARRE, Daniel $128,656 3 Yr(s) VVP
Université de Montréal
Discovery of HCV therapeutic targets using energy transfer technology.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
50
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
LAVOIE, Josée G BROWNE, Annette J / ENI, Rachel / KAUFERT, Joseph M / O'NEIL, John D
 $132,504 3 Yr(s) ABH
University of Northern British Columbia
Leaving for the city: An assessment of cultural social, health and economic dimensions of Manitoba First Nations relocating to urban centres to access medical care
LE MELLEDO, Jean-Michel ALLEN, Peter S / BAKER, Glen B / HANSTOCK, Christopher C / NEWMAN, Stephen C
 $152,553 3 Yr(s) GSH
University of Alberta
Assessment of brain neurochemical alterations with postpartum depression (PPD)
LECLAIR, Robert $58,786 3 Yr(s) MPI
Laurentian University of Sudbury
An energy dispersive x-ray diffraction tool to diagnose cancers in breast biopsies
LECOMTE, Roger
BENARD, Francois / BENTOURKIA, M'Hamed
 $107,289 5 Yr(s) MPI
Université de Sherbrooke
Imagerie moléculaire multimodale à haute résolution sur modèle animal: un nouvel outil polyvalent pour la recherche biomédicale
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
51
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
LECOMTE, Tania BRINK, Johann H / HONER, William G / KANG, G. Shimi K / LANG, Donna J / MACEWAN, William G / MUESER, Kim T / THORNTON, Allen E
 $68,818 2 Yr(s) PSB
GOLDNER, Elliot M
Université de Montréal
Simon Fraser University (Burnaby, B.C.)
The methamphetamine and psychosis study (MAPS)
LEE, Douglas S ALTER, David A / AUSTIN, Peter C / LAUPACIS, Andreas / SCHULL, Michael J / STUKEL, Therese A / TU, Jack V / YOU, John J
 $144,730 3 Yr(s) HSI
University Health Network (Toronto)
Institute for Clinical Evaluative Sciences- Toronto
Emergent Care and Outcomes of Acute Heart Failure
LEE, Patrick W $142,330 5 Yr(s) VVP
Dalhousie University (Nova Scotia)
The Molecular Basis of Host Cell Permissiveness to Reovirus Infection
LEGAULT, Pascale $135,794 3 Yr(s) BMA
Université de Montréal
Structural and Engineering Studies of Ribozymes
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
52
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
LEHMAN, Michael N $123,464 4 Yr(s) CIA
University of Western Ontario
Prenatal programming of the reproductive neuroendocrine system
LEROUX, Jean-Christophe $83,177 4 Yr(s) PS
Université de Montréal
In situ-forming implants of rivastigmine in the treatment of Alzheimer's disease
LESSARD, Julie $132,443 5 Yr(s) DEV
Université de Montréal
Developmental Roles of Hemopoietic-Specific ATP-Dependent Chromatin Remodeling
LEVESQUE, Roger C $133,343 5 Yr(s) GMX
Université Laval
Functional genomics and characterization of genes essential for in vivo maintenace in Pseudomonas aeruginosa
LEYTON, Marco BENKELFAT, Chawki / DAGHER, Alain
 $189,709 5 Yr(s) BSB
McGill University
Neurobiology of Cocaine Addiction: Striatal and Extra-Striatal Dopamine Release in Response to Relapse Precipitants
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
53
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
LI, Ren-Ke $136,224 5 Yr(s) CSA
University Health Network (Toronto)
An angiogenic progenitor cell niche in the uterus: potential implications for cell therapy
LIGHT, Peter E $140,068 5 Yr(s) CSA
University of Alberta
Calcium homeostasis and metabolism in the diseased heart
LIPMAN, Ellen L MARZIALI, Elsa $87,943 1 Yr(s)
6 Mths
 HSI
McMaster University
Web-based Mental Health Services for At-Risk Women: A Pilot Study
LIU, Lixin $107,647 3 Yr(s) CSC
University of Saskatchewan
LSP1 signaling mechanisms in chemokine- induced neutrophil emigration
LIX, Lisa M BOWMAN, Christopher S / HOBSON, Douglas E / LESLIE, William D / QUAN, Hude / ROOS, Leslie L / TARGOWNIK, Laura E / WANG, Liqun
 $67,945 3 Yr(s) PUB
University of Manitoba
Classification Algorithms to Distinguish Chronic Disease Cases from Non-Cases in Administrative Data
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
54
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
LOISELLE, Marguerite DUGRÉ, Suzanne / GRENIER, Stéphane / MARCEAU, Richard / POTVIN, Micheline
 $106,067 3 Yr(s) ABH
Direct Payment
Université du Québec en Abitibi- Témiscamingue
Le retour des jeunes enfants dans la communauté algonquine de Kitcisakik: une recherche action visant l'engagement de la commuanauté envers la santé et le bien-être des enfants.
LU, Rui (Ray) $113,195 5 Yr(s) VVP
University of Guelph
Biological function(s) of Luman in human cellular processes and its potential role in herpesvirus infection
MAGHNI, Karim WELMAN, Mélanie $104,680 4 Yr(s) RS
LEMIERE, Catherine
MALO, Jean-Luc
Hôpital du Sacré-Coeur de Montréal
Role of Tac1 and Tac1R genes in basophil function: Implications for asthma
MAK, Tak W HAO, Zhenyue $131,795 5 Yr(s) IT
University Health Network (Toronto)
Mechanisms of Cell Survival and Apoptosis in Immune System Cells
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
55
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
MAK, Tak W $153,480 5 Yr(s) MCC
University Health Network (Toronto)
Princess Margaret Hospital (Toronto)
The roles of PTEN and PI3'K signalling components in tumorigenesis
MAK, Tak W ARPAIA, Enrico $148,998 5 Yr(s) MCC
University Health Network (Toronto)
Influence of alterations to the cell's cytoskeleton on tumour cell metastasis.
MAKRIGIANNIS, Andrew P CARLYLE, James R $132,586 5 Yr(s) IT
Institut de recherches cliniques de Montréal
Genetic investigation of MHC-independent missing-self recognition by natural killer cells
MANJUNATH, Puttaswamy $117,031 2 Yr(s)
6 Mths
 E
Hôpital Maisonneuve-Rosemont (Montréal)
Insights into the mechanisms underlying fertility: Role of novel phospholipid-binding proteins in sperm function
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
56
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
MARCEL, Yves L $133,388 5 Yr(s) M
University of Ottawa
University of Ottawa Heart Institute
Apolipoprotein A-I lipidation and HDL genesis
MARCHAND, André BELANGER, Claude / BOUCHARD, Stephane / DUGAS, Michel J / GOSSELIN, Patrick / LABRECQUE, Joane / LANGLOIS, Frederic
 $74,585 5 Yr(s) BSB
Université du Québec à Montréal
Centre de recherche Fernand-Seguin de l'Hôpital Louis H.- Lafontaine (Mtl)
The Effect of a Combined versus a Conventional Cognitive-Behavioral Treatment for Comorbid Generalized Anxiety Disorder and Panic Disorder with Agoraphobia
MARTEL, Sylvain BEAUDOIN, Gilles / GABOURY, Louis / LEROUX, Jean-Christophe / SOULEZ, Gilles / YAHIA, L'Hocine
 $72,971 3 Yr(s) BME
École polytechnique de Montréal
MRI Based Targeting of Therapeutic Magnetic Micro Carriers for Chemoembolization of Liver Tumors
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
57
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
MARTIN, Ruth E BUCHANAN-ARVAY, Marla / BUXTON, Jane / CONDELLO, Lara-Lisa / CORNEIL, Trevor A / DESMARAIS, Sarah L / FAIRBROTHER, Nichole / FELS, Lynn M / FRANKISH, Charles J / GRANGER-BROWN, Alison J / LEGGO, Carl / MACAULAY, Ann C / OGILVIE, Gina S / RAMSDEN, Vivian R / SHANNON, Kate / WARDMAN, Dennis A
 $124,023 3 Yr(s) GSH
JANSSEN, Patricia A
University of British Columbia
Undetermined
Doing Time: A Time for Incarcerated Women to Develop an Action Health Strategy
MASSON, Jean-Yves $141,212 5 Yr(s) MCC
Université Laval
Centre de recherche de L'Hôtel-Dieu de Québec
Roles of homologous recombination proteins in DNA double-strand break repair and genome stability
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
58
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
MATHESON, Kimberly FOSTER, Mindi D $140,566 5 Yr(s) PSB
ANISMAN, Hymie
Carleton University (Ottawa)
The cumulative impacts of everyday discrimination: Altered neuroendocrine and cytokine functioning and vulnerability to stress- related psychopathology.
MATHIEU, Patrick DESPRES, Jean-Pierre / LAROSE, Eric / PICARD, Frédéric
 $89,472 5 Yr(s) CSB
PIBAROT, Philippe J
Université Laval
Institut universitaire de cardiologie et pneumologie de Québec
Implication of atherosclerotic pathways and metabolic risk factors in the structural deterioration of bioprosthetic heart valves
MATSUUCHI, Linda $124,012 5 Yr(s) IT
University of British Columbia
Signaling by the antigen receptor on B lymphocytes (BCR)
MCGLADE, Catherine J $179,574 5 Yr(s) MCC
Hospital for Sick Children (Toronto)
Role of the SLAP adaptor proteins in ubiquitin dependent regulation of receptor tyrosine kinases.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
59
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
MCISAAC, Warren J MAZZULLI, Tony / MOINEDDIN, Rahim
 $73,431 3 Yr(s) MI
Mount Sinai Hospital (Toronto)
A National Study Of Community-Acquired Antibiotic Resistant E.Coli Causing Uncomplicated Urinary Tract Infections In Adult Women
MCKEEVER, Patricia D DOHERTY, Sean T / DUNN, James R / YANTZI, Nicole / YOUNG, Nancy L
 $120,256 3 Yr(s) CHI
RUDDICK, Susan M
Bloorview Kids Rehab (Toronto)
School, Home and Neighbourhood Accessibility: Physically Disabled Children's Assessments (The ScHaN Project)
MCKINNEY, Rebecca A
$146,076 3 Yr(s) NSB
McGill University
The functions of dendritic spine shape and motility in the hippocampus
MCPHERSON, Peter S $90,336 5 Yr(s) CBM
McGill University
Montreal Neurological Institute
Intracellular membrane trafficking in health and disease
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
60
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
MCWILLIAMS, Annette M LAM, Stephen / MACAULAY, Calum E
 $102,158 3 Yr(s) CBT
University of British Columbia
BC Cancer Agency (Vancouver, BC)
Detection of Lung Cancer using an Electronic Nose
MEANEY, Michael J $125,662 5 Yr(s) BSA
Douglas Hospital Research Centre (Verdun, Québec)
The neurobiology of individual differences in maternal behaviour in the rat
MICHELAKIS, Evangelos D $145,837 3 Yr(s) CSC
University of Alberta
The metabolic basis of vascular remodeling in pulmonary hypertension
MIEDEMA, Baukje LAMBERT-LANNING, Anita / LEMIRE, Francine L / MANCA, Donna P / RAMSDEN, Vivian R / TATEMICHI, Sue R
 $51,172 3 Yr(s) HPM
Dalhousie University (Nova Scotia)
Dr. Everett Chalmers Hospital (Fredericton)
Family Physicians and Workplace Abusive/Violent Encounters: Prevalence, Incidence, Impact and Strategy.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
61
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
MILLER, Wilson H PETTERSSON, Filippa $138,305 5 Yr(s) CBT
Jewish General Hospital (Montreal)
Lady Davis Institute for Medical Research (Mtl)
Novel mediators of response and resistance to epigenetic therapy of leukemia
MINCHINTON, Andrew I $127,686 4 Yr(s) CPT
University of British Columbia
B.C. Cancer Research Centre (Vancouver)
Extravascular distribution of anticancer drugs
MITCHELL, Grant A $129,333 4 Yr(s) G
Hôpital Sainte-Justine (Montréal)
An Integrated Approach to Diseases of Coenzyme A Ester Metabolism
MOFFAT, Jason $156,015 5 Yr(s) GMX
University of Toronto
Functional identification of genes required for cellular adaptive evolution during nutrient/metabolic stress.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
62
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
MOHN, William W AV-GAY, Yossef $108,585 5 Yr(s) MI
University of British Columbia
Mycobacterial cholesterol metabolism: A key piece in the pathogenesis puzzle?
MONEY, Deborah M BITNUN, Sean A / COTE, Hélène / COUTLÉE, François / DOBSON, Simon R / FORBES, John C / KLEIN, Marina B / KOLLMANN, Tobias R / KRAJDEN, Mel / LOUTFY, Mona R / OGILVIE, Gina S / PETRIC, Martin / PICK, Neora / RABOUD, Janet M / RACHLIS, Anita R / SMAILL, Fiona M / STUART, Gavin C / VAN SCHALKWYK, Julianne E / WALMSLEY, Sharon L / WOBESER, Wendy L
 $277,809 5 Yr(s) PUB
University of British Columbia
Children's & Women's Health Centre of British Columbia
A Study of an HPV VLP Vaccine in a Cohort of HIV Positive Girls and Women
MONTPLAISIR, Jacques Y MONCHI, Oury / POSTUMA, Ronald B / SOUCY, Jean-Paul
 $127,558 5 Yr(s) BSC
GAGNON, Jean-François
Hôpital du Sacré-Coeur de Montréal
Diagnostic, pathophysiologie et traitement du trouble comportemental en sommeil paradoxal
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
63
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
MOODIE, Erica E KRAMER, Michael S / PLATT, Robert W / SUISSA, Samy
 $95,059 3 Yr(s) PUB
McGill University
Statistical methods for causal inference in longitudinal studies with non-compliance and missing data
MORIDE, Yola ABRAHAMOWICZ, Michal M / BATTISTA, Renaldo N / GALBAUD DU FORT, Guillaume / GREENFIELD, Brian J / KOZYRSKYJ, Anita L / LELORIER, Jacques / LYND, Larry D / METGE, Colleen J / PERREAULT, Sylvie S
 $110,336 2 Yr(s) PUB
Université de Montréal
Antidepressants and risk of suicide or self-harm in Canadian youth: A national population-based study
MOROY, Tarik $116,719 3 Yr(s) BMB
Institut de recherches cliniques de Montréal
The role of alternative splicing in the regulation of T-cell function
MOUGINOT, Didier M $95,683 5 Yr(s) NSA
Université Laval
Centre hospitalier de l'Université Laval (Québec)
Hypothalamic sodium sensor in salt appetite and osmoregulation
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
64
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
MULLIGAN, Sean J $76,699 3 Yr(s) NSB
University of Saskatchewan
Bidirectional Communication Between Astrocytes and the Cerebrovasculature
MURRAY, Allan G $117,043 3 Yr(s) CSC
University of Alberta
Lymphocyte-endothelial cell interactions in inflammation
NAGANO, Makoto $133,026 5 Yr(s) E
The Research Institute of the McGill University Health Centre
The regulatory mechanism of spermatogonial stem cell proliferation and differenitation
NAVARRE, William W $118,306 5 Yr(s) MI
University of Toronto
The role of H-NS and related molecules in regulating bacterial virulence gene expression
NEWBOLD, Kenneth B BIRCH, Stephen / EYLES, John D / WILSON, Kathleen J
 $62,083 3 Yr(s) HPM
McMaster University
Journey to health: An investigation of the social production of health and access to care within hamilton's refugee community
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
65
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
NGUYEN, Peter V $109,757 5 Yr(s) NSB
University of Alberta
Modulation of Synaptic Plasticity and Memory by Beta-Adrenergic Receptors
NISLOW, Corey E HUGHES, Timothy R $158,802 4 Yr(s) GMX
University of Toronto
Genome-wide determinants of nucleosome occupancy and promoter definition
OREMUS, Mark RAINA, Parminder S $226,799 2 Yr(s) HPM
TARRIDE, Jean-Eric
McMaster University
An assessment of Canadians' willingness-to-pay for Alzheimer's disease medications: patients, caregivers, and the general public.
ORLOWSKI, John $169,223 5 Yr(s) CP
McGill University
Function and Regulation of Neural Sodium/Proton Exchangers
ORSER, Beverley A $165,261 5 Yr(s) NSA
University of Toronto
Tonic GABAergic regulation of memory and plasticity
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
66
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
OSBORNE, Lucy R MINASSIAN, Berge A $109,957 5 Yr(s) G
University of Toronto
Characterization of genetic and molecular mechanisms underlying infantile spasms, a common and catastrophic form of epilepsy in infants
OUDIT, Gavin Y $123,453 5 Yr(s) CSB
University of Alberta
Role of Angiotensin Converting Enzyme 2 (ACE2) in Heart Disease: using human recombinant ACE2 as Potential Therapy
OXLAND, Thomas R KOZLOWSKI, Piotr / KWON, Brian K / TETZLAFF, Wolfram G
 $155,060 5 Yr(s) BME
University of British Columbia
Vancouver Coastal Health Research Institute
Clinically relevant mechanisms of spinal cord injury
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
67
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
PADWAL, Raj S BIRCH, Daniel W / FASSBENDER, Konrad / MCCARGAR, Linda J
 $123,111 4 Yr(s) HSR
KLARENBACH, Scott
MAJUMDAR, Sumit R
SHARMA, Arya M
University of Alberta
Royal Alexandra Hospital (Edmonton)
A Population-based, Prospective Controlled Evaluation of the Clinical, Economic and Humanistic Outcomes Associated with Bariatric Surgery
PAI, Emil F $118,250 3 Yr(s) BMA
University Health Network (Toronto)
Structural and Functional Analysis of Proteins Involved in Mg-homeostasis
PANTOPOULOS, Konstantinos $128,656 5 Yr(s) EM
Jewish General Hospital (Montreal)
Lady Davis Institute for Medical Research (Mtl)
Iron metabolism in health and disease: The IRE/IRP system and beyond
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
68
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
PANTOPOULOS, Konstantinos $154,672 3 Yr(s) CBM
Jewish General Hospital (Montreal)
Lady Davis Institute for Medical Research (Mtl)
The role of soluble hemojuvelin in systemic iron homeostasis
PARADIS, Hélène $121,612 4 Yr(s) BCA
GENDRON, Robert L
Memorial University of Newfoundland
Tubedown in vision loss during aging and age- related retinopathies
PATEL, Kamala D
$135,042 5 Yr(s) RS
University of Calgary
Mechanotransduction in Leukocyte Trafficking
PELCHAT, Martin $89,569 5 Yr(s) VVP
University of Ottawa
Mechanism of recognition of the hepatitis delta virus RNA promoters by the human RNA- polymerase II
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
69
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
PERETZ, Isabelle S $118,949 5 Yr(s) BSC
Université de Montréal
Amusia: from behavior to brain, genes and plasticity
PETERS, Terence M DRANGOVA, Maria / GUIRAUDON, Gerard M / JONES, Douglas L
 $116,913 5 Yr(s) MPI
Robarts Research Institute - U.W.O. (London, Ont.)
Image-guidance for minimally-invasive cardiac procedures
PETRIDES, Michael $140,419 5 Yr(s) BSC
McGill University
Montreal Neurological Institute
Comparative study of the human and monkey cortex
PETRIK, Jim J MOOREHEAD, Roger A $92,536 3 Yr(s) CPT
University of Guelph
Thrombospondin-1 as an inibitor of epithelial ovarian cancer
PIN, Christopher L $127,480 5 Yr(s) CBM
University of Western Ontario
Signaling networks in pancreatic disease
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
70
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
POIRIER, Donald LIN, Sheng-Xiang $114,056 4 Yr(s) PS
Université Laval
Centre hospitalier de l'Université Laval (Québec)
Inhibiteurs des isoformes 1, 3 et 12 de la 17beta-HSD à double action (sélectifs et sans activité résiduelles sur ER et AR) pour contrôler les niveaux d'estrogènes et d'androgènes dans les tumeurs cancéreuses du sein et de la prostate
POIRIER, Guy G HENDZEL, Michael J / MASSON, Jean-Yves
 $181,202 5 Yr(s) CBT
Université Laval
Centre hospitalier de l'Université Laval (Québec)
Signalling functions of poly(ADP-ribosyl)ation in the DNA damage response and cancer.
POITOUT, Vincent $122,239 3 Yr(s) M
Centre Hosp. de l'Université de Montréal (CHUM)
The role of GPR40 and GPR120 in pancreatic beta-cell function
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
71
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
POST, Martin $123,795 5 Yr(s) RS
KAVANAGH, Brian Patrick W
MCKERLIE, Colin
PACE-ASCIAK, Cecil R
Hospital for Sick Children (Toronto)
Therapeutic potential of anti-inflammatory Hepoxilin analogs
POULIOT, Roxane POUBELLE, Patrice- Édouard
 $94,550 3 Yr(s) CIB
Université Laval
Hôpital du Saint-Sacrement (Québec)
Comprendre la différenciation cellulaire accélérée des kératinocytes psoriasiques grâce au génie tissulaire
PRAKASH, Satya ALAOUI-JAMALI, Moulay A
 $121,100 3 Yr(s) CBT
McGill University
Development of a novel receptor targeted drug delivery system for metastatic breast cancers using polymeric membrane drug-functionalized carbon nanotubes.
PRAUD, Jean-Paul $131,363 5 Yr(s) RS
Université de Sherbrooke
Laryngeal function and neonatal respiration
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
72
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
RAHME, Elham BERNATSKY, Sasha R / BERRY, Gregory K / DASGUPTA, Kaberi / KAHN, Susan R
 $90,636 3 Yr(s) POP
The Research Institute of the McGill University Health Centre
Risk-benefit ratio of extended thromboprophylaxis to prevent venous thromboembolism among patients undergoing hip or knee replacement surgery: An administrative database validity study
RAINVILLE, Pierre GOFFAUX, Philippe / PICHE, Mathieu / POTVIN, Stéphane
 $134,375 5 Yr(s) BSC
MARCHAND, Serge
Institut universitaire de gériatrie de Montréal
Electrophysiology and brain imaging of normal and abnormal pain modulatory systems
RAMANATHAN, Sheela $100,742 5 Yr(s) IT
Université de Sherbrooke
Regulation of apoptotic cell death in T lymphocytes by GIMAP5
RASSART, Eric $148,251 5 Yr(s) VVP
Université du Québec à Montréal
Murine leukemia viruses : molecular characterization and search for oncogenes
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
73
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
RATHBONE, Michel P SALEH, Tarek M $124,919 2 Yr(s) CSB
JIANG, Shucui
McMaster University
Neuroprotective properties of guanosine in experimental stroke
REIMER, Raylene A $97,075 3 Yr(s) NUT
University of Calgary
Dietary modulation of integrated gut hormone response to manage obesity
RENNIE, Paul S CULLIS, Pieter R $150,500 3 Yr(s) E
University of British Columbia
In vivo siRNA knockdown of androgen receptors to treat advanced prostate cancer
RIABOWOL, Karl T $158,573 5 Yr(s) BCA
University of Calgary
The Role of Lamins in ING Family Function
RICHARDSON, Chris G JOHNSON, Joy L / PRKACHIN, Kenneth M
 $338,004 3 Yr(s) PSB
RATNER, Pamela A
University of British Columbia
The British Columbia Adolescent Substance Use Survey
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
74
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
ROBAIRE, Bernard $150,202 5 Yr(s) GSH
McGill University
Androgen action in the epididymis
ROCHELEAU, Christian E $124,663 3 Yr(s) CBM
McGill University
Analysis of a putative Rab GTPase activating protein in endocytic trafficking
ROCHETTE, Annie JAMIESON, Isabelle / LEFEBVRE, Helene / RACINE, Eric
 $67,963 2 Yr(s) ELH
Université de Montréal
Besoins des proches, implication dans les soins et services de santé et enjeux éthiques post- accident vasculaire cérébral (AVC) selon trois perspectives: proches, personnes ayant subi l'AVC et professionnels de la santé
RONEN, Gabriel M BOYLE, Michael H / CUNNINGHAM, Charles E / LACH, Lucyna M / ROSENBAUM, Peter L / STREINER, David L
 $153,497 5 Yr(s) PSD
McMaster University
Outcome Trajectories in Children with Epilepsy: What Factors are Important?
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
75
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
ROSE, Ann Marie HIETER, Philip A $125,388 5 Yr(s) BMB
University of British Columbia
Genetic interactions with chromosome instability mutants in C. elegans to identify new anti-tumour targets
ROSE, Kenneth P $171,090 5 Yr(s) MOV
Queen's University (Kingston, Ontario)
Input-output properties of neck motoneurons: The role of dendritic structure
ROSS, Robert M ADAMS, Michael A / JANISZEWSKI, Peter M / MORALES, Alvaro / TSCHAKOVSKY, Michael E
 $100,977 3 Yr(s) GSH
Queen's University (Kingston, Ontario)
Acute and Chronic Exercise as Treatment Strategies for Erectile Dysfunction in Obese Men
ROSYCHUK, Rhonda J
KLASSEN, Terry P / ROWE, Brian H / SENTHILSELVAN, Ambikaipakan / VOAKLANDER, Donald C
 $83,173 1 Yr(s)
6 Mths
 HSR
University of Alberta
Respiratory presentations to Alberta emergency departments: Description and detection of clusters
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
76
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
ROTIN, Daniela $139,836 5 Yr(s) RS
Hospital for Sick Children (Toronto)
Role of Nedd4 proteins in lung function and development
ROTIN, Daniela $166,837 5 Yr(s) CBM
Hospital for Sick Children (Toronto)
Biological Functions of the Protein Tyrosine Phosphatase, PTPsigma
ROTTAPEL, Robert K $134,561 3 Yr(s) CIB
University Health Network (Toronto)
Ontario Cancer Institute (Toronto)
The adapter protein SH3BP2, encoded by the Cherubism Locus, regulates both OSTEOclast and OSTEOblast function
ROUILLER, Isabelle $110,901 5 Yr(s) BMA
McGill University
Structural and functional analyses of the mechanisms of protein penetration through membranes.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
77
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
ROULEAU, Guy A $168,103 5 Yr(s) NSA
Centre Hosp. de l'Université de Montréal (CHUM)
The role of mutated WNK1 (WNK1/HSN2) neuronal specific isoform in HSANII
ROULEAU, Guy A GASPAR, Claudia C $166,054 5 Yr(s) G
Centre Hosp. de l'Université de Montréal (CHUM)
Molecular Investigation of Expanded CAG Repeat Toxicity
ROUSSEAU, François BUREAU, Alexandre / COLE, David E / DODIN, Sylvie / LAFLAMME, Nathalie
 $150,869 2 Yr(s) G
Université Laval
High density polymorphisms analysis of candidate genes involved in osteoporosis, bone remodeling and homeostasis.
ROZEN, Rima CHRISTENSEN, Karen E $86,000 2 Yr(s) NUT
The Research Institute of the McGill University Health Centre
Trifunctional folate-metabolizing enzyme MTHFD1: impact on birth defects and cancer
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
78
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
RUDNER, Adam D $116,484 5 Yr(s) CP
University of Ottawa
Control of the function and activity of the anaphase promoting complex by phosphorylation
SANCHE, Léon HUNTING, Darel J / WAGNER, James R
 $141,649 5 Yr(s) MPI
Université de Sherbrooke
Secondary electron collision cross sections for use in radiotherapy and radioprotection. Sections efficaces de diffusion des électrons secondaires pour utilisation en radiothérapie et radioprotection.
SARRET, Philippe MELIK PARSADANIANTZ, Stéphane T
 $102,511 3 Yr(s) PT
Université de Sherbrooke
Les chimiokines : Nouvelles cibles thérapeutiques dans le traitement de la douleur.
SCHAFFER, Ayal CAIRNEY, John / CHEUNG, Amy H / KURDYAK, Paul A / LEVITT, Anthony J
 $36,625 2 Yr(s) BSB
Sunnybrook Health Sciences Centre
An Epidemiological Comparison of Bipolar Disorder and Major Depressive Disorder: Implications for Improving Diagnosis and Management
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
79
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
SCHMITT, Estelle M $101,724 3 Yr(s) CBT
Centre Hosp. de l'Université de Montréal (CHUM)
Spatial coordination of DNA-damage response network: The centrosomal regulation of G2/M cell cycle checkpoint.
SCHRADER, John W PAI, Emil F $93,138 5 Yr(s) IT
University of British Columbia
Structural investigations into the innate foundations of human antibody responses to vulnerable sites on common pathogens
SCHRADER, John W $114,441 5 Yr(s) MCC
University of British Columbia
Molecular characterization of the role of the elevated levels of M-Ras in cancer
SCHWARTZMAN, Kevin BENEDETTI, Andrea / GREENAWAY, Christina A / MENZIES, Richard / VISSANDJEE, Bilkis
 $59,973 4 Yr(s) PSB
The Research Institute of the McGill University Health Centre
McGill University
What's the damage? Impact of tuberculosis disease, infection, and treatment on health status
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
80
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
SCOTT, Ian C $129,000 5 Yr(s) CSA
Hospital for Sick Children (Toronto)
Genetic and cellular analysis of the role of Agtrl1b in myocardial progenitor development.
SEGUELA, Philippe A $132,010 5 Yr(s) CP
McGill University
Physiologie moléculaire des récepteurs-canaux P2X dans les neurones de la douleur
SEVIGNY, Andrée DUMONT, Serge / GUIRGUIS-YOUNGER, Manal / TOURIGNY, André
 $74,834 3 Yr(s) PLC
AUBIN, Michèle
Université Laval
L'étude dynamique des facteurs facilitant et contraignant le bénévolat auprès des aînés en fin de vie qui vivent à domicile
SHARKEY, Keith A DAVISON, Joseph S / PATEL, Kamala D / PITTMAN, Quentin J
 $125,054 5 Yr(s) EM
University of Calgary
Endocannabinoids in the regulation of gastrointestinal motor function
SHI, Yan $65,231 3 Yr(s) IT
University of Calgary
Purine in Immune Regulation
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
81
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
SHIZGAL, Peter PENHUNE, Virginia B / PLOURDE, Gilles
 $120,770 5 Yr(s) BSA
Concordia University (Montreal, Quebec)
Neural correlates of thermal comfort and discomfort: functional magnetic resonance imaging.
SHRIER, Alvin YOUNG, Jason C $123,035 5 Yr(s) CSA
McGill University
Mechanisms of hERG trafficking
SIMUNOVIC, Marko CADEDDU, Margherita O / CHARLES, Cathy A / GUYATT, Gordon H / STRAUS, Sharon E / SUTRADHAR, Rinku / THABANE, Lehana / URBACH, David R
 $144,765 3 Yr(s) HSR
BAXTER, Nancy N
McMaster University
Juravinski Cancer Centre (Hamilton, ON)
Assessing the uptake and effectiveness of laparoscopic surgery for colorectal cancer in Ontario
SINGH, Gurmit GERSTEIN, Hertzel C / LAFLAMME, Pierre / PINTHUS, Jehonathan H
 $120,400 5 Yr(s) PS
McMaster University
Juravinski Cancer Centre (Hamilton, ON)
Reactive oxygen species: A link between hyperglycemia and cancer.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
82
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
SIU, K. W. Michael COLGAN, Terence J / MACMILLAN, Christina M / RALHAN, Ranju / WITTERICK, Ian
 $126,764 3 Yr(s) CPT
York University (Toronto, Ontario)
Discovery, Identification and Verification of Novel Biomarkers in Head and Neck Cancer
SLED, John G HENKELMAN, R. Mark $96,620 3 Yr(s) MPI
Hospital for Sick Children (Toronto)
Cerebral vascular degeneration
SLIM, Rima QURESHI, Salman T / SALEH, Maya
 $117,793 3 Yr(s) G
The Research Institute of the McGill University Health Centre
Elucidation of the molecular mechanisms responsible for hydatidiform moles
SMITH, Carlyle T FELDMAN, Howard / PETERS, Kevin R
 $76,103 5 Yr(s) BCA
Trent University (Peterborough, Ontario)
Sleep states, memory and aging
SMITH, Francine G $135,949 5 Yr(s) CSB
University of Calgary
Blood volume regulation during ontogeny
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
83
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
SMYLIE, Janet K ABONYI, Sylvia / ANDERSON, Marcia J / BURNS, Roberta Z / CAMPBELL, Maria / DEWAR, Jonathan / MACDOUGALL, Brenda / MARACLE, Sylvia / MCSHANE, Kelly / O'CAMPO, Patricia / STERLING, Lisa S / WHEELER, Winona L / WOLFE, Sara H
 $186,638 5 Yr(s) ABH
St. Michael's Hospital (Toronto)
Indigenous Knowledge Network for Infant, Child, and Family Health
SOMA, Kiran K $135,929 5 Yr(s) BSA
University of British Columbia
Neuroendocrine regulation of aggressive behaviour and adult neuroplasticity
SOMERS, Gino R ZIELENSKA, Maria $91,564 3 Yr(s) CPT
Hospital for Sick Children (Toronto)
Pediatric undifferentiated soft tissue sarcomas - a model for understanding the mechanisms underlying sarcoma development
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
84
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
SONENBERG, Nahum $159,361 5 Yr(s) CP
McGill University
Physiology of translational control by Paips - modulators of poly(A)-binding protein.
SOON, Judith A HANLON, Neil T / JOHNSON, Joy L / KELM, Mary-Ellen / SHOVELLER, Jean A
 $90,867 2 Yr(s) GSH
University of British Columbia
Experiences with contraception among youth in northern BC: Examining the impact of gender, place and culture
SOSSI, Vesna FLORESCO, Stanley B / MCKEOWN, Martin J / STOESSL, A. Jonathan / YOUNG, Allan H
 $96,896 3 Yr(s) BSB
University of British Columbia
Investigation of treatment related compulsive behaviours and impulse control disorders in Parkinson's disease
ST-AMANT, Louis
$87,229 5 Yr(s) NSB
Université de Montréal
The genetic basis and role of spontaneous activity in vertebrate motor network development.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
85
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
STANLEY, Elise F $165,442 5 Yr(s) NSA
University Health Network (Toronto)
Toronto Western Research Institute (Toronto)
The Presynaptic Transmitter Release Site Organelle
STANLEY, Elise F $138,906 5 Yr(s) NSB
University Health Network (Toronto)
Toronto Western Research Institute (Toronto)
Nanophysiology of fast transmitter release.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
86
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
STEVENS, Bonnie J BARWICK, Melanie A / CAMPBELL, Fiona / CHAMBERS, Christine T / COHEN, Janice S / CUMMINGS, Greta / ESTABROOKS, Carole Anne / FINLEY, G. A / JOHNSTON, Celeste / KAVANAGH, Patricia M / LATIMER, Margot A / LEE, Shoo K / LEMAY, Sylvie / MCGRATH, Patrick J / RASHOTTE, Judith M / ROSMUS, Christina B / SAWATZKY-DICKSON, Doris / SCOTT, Shannon D / SIDANI, Souraya / STINSON, Jennifer N / STREMLER, Robyn L / SYNNES, Anne R / TADDIO, Anna / VILLENEUVE, Edith / WARNOCK, Fay F / WILLAN, Andrew R / YAMADA, Janet
 $344,988 4 Yr(s) KTE
Hospital for Sick Children (Toronto)
Translating Research on Pain in Children (TROPIC) Study
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
87
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
STIELL, Ian G BREHAUT, Jamie C / DAVIES, Barbara L / GRIMSHAW, Jeremy M / O'CONNOR, Annette M / PERRY, Jeffrey J / WELLS, George A
 $78,677 2 Yr(s) HSR
Ottawa Health Research Institute
Evaluation of the Safety of C-Spine Clearance by Emergency Department Triage Nurses (Phase IV)
STONE, Laura S $100,403 5 Yr(s) PT
McGill University
Seven-transmembrane domain receptors in pain and analgesia: actions and interactions
STRACHAN, Patricia H ARTHUR, Heather M / CARROLL, Sandra L / SCHWARTZ, Lisa J
 $45,990 2 Yr(s) PSB
McMaster University
Exploring patients' decisions regarding implantable defibrillators for primary prevention
STRAUSS, Bradley H DICK, Alexander J / FOSTER, F. S / GOERTZ, David E / WRIGHT, Graham A
 $159,100 3 Yr(s) CSB
Sunnybrook Health Sciences Centre
Therapeutic Strategies for Chronic Total Occlusion Revascularization
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
88
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
SUNG, Lillian ALLEN, Upton D / BEYENE, Joseph
 $145,526 4 Yr(s) CIA
Hospital for Sick Children (Toronto)
Predicting The Risk of Infection In Children Receiving Chemotherapy For Acute Myeloid Leukemia
TABORI, Uri $128,604 3 Yr(s) CPT
Hospital for Sick Children (Toronto)
Prognostic and therapeutic implications for telomere maintenance and telomerase inhibition in pediatric high grade gliomas
TAGALAKIS, Vicky BLOSTEIN, Mark D / HANLEY, James A / KAHN, Susan R / OPATRNY, Lucie
 $64,400 2 Yr(s) POP
Jewish General Hospital (Montreal)
Lady Davis Institute for Medical Research (Mtl)
The effect of warfarin use on the risk of prostate cancer death
TAKETO, Teruko $133,364 3 Yr(s) GSH
The Research Institute of the McGill University Health Centre
Failure in the second meiotic division in the mouse oocyte
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
89
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
TANGUAY, Robert M $120,400 4 Yr(s) EM
Université Laval
Molecular analysis of the liver pathologies associated with tyrosinemia
TEODORO, Jose G $116,478 5 Yr(s) VVP
McGill University
Role of the Anaphase Promoting Complex in Cancer and Viral Infection
TEODORO, Jose G $134,915 3 Yr(s) CPT
McGill University
Characterization of novel mechanisms of angiogenesis inhibition
TER KEURS, Hendrik E $120,842 3 Yr(s) CSB
University of Calgary
Reduced Force of the Heartbeat in Congestive Heart Failure: Dysfunctional Ca2+ Transport
TESSON-RULKO, Frédérique STEWART, Alexandre F $206,343 3 Yr(s) CSC
LEENEN, Frans H
University of Ottawa
University of Ottawa Heart Institute
Genetic basis of salt sensitive hypertension in humans.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
90
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
THOMAS-STONELL, Nancy L ODDSON, Bruce / ROSENBAUM, Peter L
 $92,063 3 Yr(s) CHI
Bloorview Kids Rehab (Toronto)
Focus on the Outcomes of Communication Under Six (the FOCUS): Evaluating Validity and Responsiveness to Change
TINMOUTH, Alan T CALLUM, Jeannie L / FERGUSSON, Dean A / GRIMSHAW, Jeremy M / HEBERT, Paul C / MCINTYRE, Laura-Lyn A / RAMSAY, Timothy O / SHOJANIA, Kaveh G / WEBERT, Kathryn E
 $183,430 1 Yr(s)
6 Mths
 HSR
Ottawa Health Research Institute
Ottawa Hospital General Campus (Ottawa Ontario)
Appropriateness of Frozen Plasma Use in Canada
TIRONA, Rommel G KIM, Richard B $105,570 3 Yr(s) PS
University of Western Ontario
Role of Skeletal Muscle Transporters in Statin- Induced Myopathy
TONELLI, Marcello A DAVISON, Sara / GILL, John S / HEMMELGARN, Brenda R / KLARENBACH, Scott / MANNS, Braden J / PANNU, Neesh I / WIEBE, Natasha / YEATES, Karen
 $130,476 5 Yr(s) PUB
University of Alberta
Role of residence location in the care of elderly Canadians with kidney failure
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
91
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
TRIGATTI, Bernardo L $132,169 3 Yr(s) CSC
McMaster University
Role of SR-BI in the vascular wall in protection against occlusive coronary artery atherosclerosis and myocardial fibrosis in a unique mouse model.
TRON, Victor A ALLEN, Theresa M / ANDREW, Susan E
 $137,455 3 Yr(s) CPT
Queen's University (Kingston, Ontario)
Targeting anti-apoptotic Bcl-2 family members in malignant melanoma
TUPLING, Allan R $60,000 2 Yr(s) MOV
University of Waterloo (Ontario)
Effects of Altered Ca2+ Pumping Efficiency of Sarco(endo)plasmic Reticulum Ca2+-ATPases on Metabolic Rate and Muscle Contractile Function
TYNDALE, Rachel F $178,880 5 Yr(s) PT
University of Toronto
Pharmacogenetics: CYP genetic variants alter smoking
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
92
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
ULUDAG, Hasan DOSCHAK, Michael R / GHAHARY, Aziz
 $136,634 4 Yr(s) BME
University of Alberta
Designing Amphiphilic Polymeric Carriers of DNA for Gene Therapy
UZONNA, Jude E $140,175 3 Yr(s) MI
University of Manitoba
Development, maintenance and loss of established anti-Leishmania immunity.
VACHER, Jean $138,630 2 Yr(s) CIB
Institut de recherches cliniques de Montréal
Molecular Analysis of Osteopetrosis
VALLIERES, Luc $117,807 4 Yr(s) CBM
Université Laval
Centre hospitalier de l'Université Laval (Québec)
Interactions between glioma cells and blood vessels
VAN DEN HURK (D.LITTEL), Sylvia $155,126 4 Yr(s) VVP
University of Saskatchewan
Role of dendritic cells in virus-induced inflammation and antigen presentation in airway tissues.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
93
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
VERGE, Valerie M $133,963 5 Yr(s) NSB
University of Saskatchewan
Sensory neuron injury, repair and maladaptive consequences: Role of neurotrophins
VIDAL, Silvia M $132,268 5 Yr(s) G
The Research Institute of the McGill University Health Centre
McGill University
Molecular genetics of host susceptibility to cardiovirulent coxsackievirus infection
VOGEL, Hans (Harm) J $126,744 5 Yr(s) BMA
University of Calgary
Molecular characterization of two unique calcium-regulatory proteins involved in hemostasis and neuronal signaling
VOHRA, Sunita BARROWMAN, Nicholas J / BUKUTU, Cecilia P / MOHER, David / SAMPSON, Margaret
 $112,594 3 Yr(s) KTE
University of Alberta
Evidence based medicine and complementary and alternative medicine: An opportunity for N- of-1 trials
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
94
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
VOLCHUK, Allen O $98,705 3 Yr(s) M
University Health Network (Toronto)
The Role of ATF6 and OASIS Endoplasmic Reticulum Stress Signaling Pathways in Pancreatic beta-Cells
WADDELL, Thomas K $112,629 5 Yr(s) RS
University Health Network (Toronto)
The role of bone marrow progenitors in lung regeneration
WANG, Rui $133,527 5 Yr(s) CSB
Lakehead University (Thunder Bay, Ontario)
CSE deficiency-related hypertension development
WANG, Yu Tian $139,556 5 Yr(s) NSA
University of British Columbia
Investigation into molecular mechanisms and physiological roles of activity-dependent AMPA receptor insertion
WANG, Yuzhuo GLEAVE, Martin E $129,000 3 Yr(s) CBT
University of British Columbia
A novel molecular target for metastatic prostate cancer therapy
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
95
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
WANG, Zhiguo $164,682 4 Yr(s) CSA
Montreal Heart Institute
MicroRNAs and Electrical, Structural and Metabolic Remodeling in Atrial Fibrillation
WANG, Zhiguo $138,761 3 Yr(s) CSB
Montreal Heart Institute
A Signature Pattern of Stress-Responsive microRNAs that Can Induce Cellular Injuries during Myocardial Infarction
WASAN, Kishor M LEON, Carlos G / SACHS- BARRABLE, Kristina / THORNTON, Sheila J
 $104,625 3 Yr(s) PS
University of British Columbia
Physiological Role of P-Glycoprotein in Regulating the Gastrointestinal Absorption and Cellular Transport of Cholesterol
WASTENEYS, Geoffrey O
$128,195 3 Yr(s) CBM
University of British Columbia
Function and control of the Tumor Overexpressed Gene class of microtubule- associated proteins: Quantitative in vivo analysis of microtubule dynamics in a plant model.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
96
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
WEEN, Jon E ALEXANDER, Michael P / STUSS, Donald T
 $35,111 2 Yr(s) BSC
Baycrest Centre for Geriatric Care (Toronto)
Fractionated frontal and executive function as a function of deep white matter stroke.
WEIJER, Charles E $77,731 4 Yr(s) ELH
University of Western Ontario
Conceptual Problems in Research Ethics IV
WEKSBERG, Rosanna CHITAYAT, David A / KEATING, Sarah J / KINGDOM, John C
 $127,961 3 Yr(s) CIA
Hospital for Sick Children (Toronto)
Investigation of Intrauterine Growth Restriction by Gene Expression and DNA Methylation Profiling
WEN, Shi Wu DAVIDGE, Sandra T / HONGZHUAN, Tan / SMITH, Graeme N / TRASLER, Jacquetta M / WALKER, Mark C / YANG, Qiuying
 $194,428 5 Yr(s) POP
Ottawa Health Research Institute
A pre-conception cohort to study preeclampsia: etiology, early biomarkers, and cardiovascular risk after childbirth.
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
97
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
WHYNE, Cari M FINKELSTEIN, Joel A $94,966 4 Yr(s) BME
YEE, Albert J
Sunnybrook Health Sciences Centre
Bone stability and tumor burden in the metastatic spine: Implications of variable disease patterns
WILD, Cameron T REHM, Juergen T / RUSH, Brian R / SOMERS, Julian / URBANOSKI, Karen A
 $149,494 3 Yr(s) PSB
University of Alberta
Social control and coercion in addiction treatment
WILSON, Alan A ADDINGTON, Jean M / HOULE, Sylvain / RUSJAN, Pablo M
 $138,226 3 Yr(s) BSB
MIZRAHI, Romina
Centre for Addiction and Mental Health (Toronto)
Stress-induced dopamine release in subjects at clinical high risk for psychosis: a [11C]-(+)- PHNO PET study
WINN, Louise M $107,539 3 Yr(s) PS
Queen's University (Kingston, Ontario)
Mechanisms of valproic acid induced teratogenesis
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
98
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
WINOCUR, Gordon HENKELMAN, R. Mark / TANNOCK, Ian F / WOJTOWICZ, Jan M
 $64,288 3 Yr(s) BSA
Trent University (Peterborough, Ontario)
An investigation of Effects of Chemotherapy on Cognitive Function in an Animal Model
WISMER, Wendy V $53,150 3 Yr(s) PLC
University of Alberta
Alberta Cancer Board (Edmonton)
A multidimensional evaluation of chemosensory perception in the advanced cancer population
WOODGETT, James (Jim) R NAGY, Andras $174,530 5 Yr(s) CBM
Mount Sinai Hospital (Toronto)
Samuel Lunenfeld Research Institute (Toronto)
Signal transduction pathways controlling cell fate determination
WRIGHT, David $60,228 3 Yr(s) NUT
University of Alberta
Control of adipose tissue mitochondrial content
WUNDER, Jay S ALMAN, Benjamin A $161,589 5 Yr(s) CBM
Mount Sinai Hospital (Toronto)
Hedgehog signaling in cartilage neoplasia and development
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
99
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
WYLIE, John L BEAUDOIN, Carole M / DAWOOD, Magdy R / VAN CAESEELE, Paul G
 $107,678 5 Yr(s) PSD
JOLLY, Ann M
University of Manitoba
The behavioural, social and cultural factors affecting the epidemiology of sexually transmitted and bloodborne pathogens in high- risk populations: Determining risk space in Canada's vulnerable populations
XING, Zhou $115,525 5 Yr(s) RS
McMaster University
Regulation of type 1 immunity by immunoreceptor DAP12 in pulmonary mycobacterial infection
YANG, Decheng $99,975 4 Yr(s) CSB
University of British Columbia
St. Paul's Hospital, Vancouver
Endoplasmic reticulum stress in coxsackievirus- induced myocarditis
YANG, Jaynie F NORTON, Jonathan $116,913 3 Yr(s) MOV
GORASSINI, Monica A
University of Alberta
Retraining walking after incomplete spinal cord injury
* "Research Institution" is displayed only when it is different from "Institution Paid".
** PRC = Peer Review Committee. A legend to the committee codes appears at the end of this list.
100
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
YEUNG, Rae S $141,738 3 Yr(s) CIB
Hospital for Sick Children (Toronto)
Kawasaki Disease: On our way to unraveling the pathogenesis
YOUSEF, George M $99,441 3 Yr(s) CPT
St. Michael's Hospital (Toronto)
Differential Expression of microRNAs in Kidney Cancer and Their Potential Utility as Cancer Biomarkers
ZETKA, Monique C $108,471 5 Yr(s) G
McGill University
Dissection of pathways regulating meiotic chromosome segregation in C. elegans
ZHANG, Shao-Ling CHAN, John S $104,036 3 Yr(s) EM
Centre Hosp. de l'Université de Montréal (CHUM)
Maternal Diabetes, Reactive Oxygen Species, Nephrogenesis and Perinatal Programming
* "Research Institution" is displayed only when it is different from "Institution Paid".
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101
Principal Investigators
Institution Paid
Research Institution*
Title
 Co-Applicant(s) Average Annual Operating Amount
 Equipment Term PRC **
Status
ZHENG, Gang BISLAND, Stuart K / WILSON, Brian C
 $150,500 3 Yr(s) CPT
University Health Network (Toronto)
Ontario Cancer Institute (Toronto)
Protease-triggered photodynamic molecular beacons for cancer imaging and treatment
ZHU, Xu-Dong $126,265 5 Yr(s) CBT
McMaster University
Functional Analysis of Proteins Involved in Telomere Length Maintenance
ZWINGMANN, Claudia $78,492 3 Yr(s) EM
Centre Hosp. de l'Université de Montréal (CHUM)
Studies on the role of glutamine synthetase nitration in Hepatic Encephalopathy following acute failure
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102
Peer Review Committees
PRC Name
ABH Aboriginal Peoples' Health
BCA Biological and Clinical Aspects of Aging
BMA Biochemistry & Molecular Biology - A
BMB Biochemistry & Molecular Biology - B
BME Biomedical Engineering
BSA Behavioural Sciences - A
BSB Behavioural Sciences - B
BSC Behavioural Sciences - C
CBM Cell Biology & Mechanisms of Disease
CBT Cancer Biology & Therapeutics
CHI Children's Health
CIA Clinical Investigation - A
CIB Clinical Investigation - B
CP Cell Physiology
CPT Cancer Progression & Therapeutics
CSA Cardiovascular System - A
CSB Cardiovascular System - B
CSC Cardiovascular System - C
DEV Developmental Biology
DS Dental Sciences
E Endocrinology
ELH Health Ethics, Law & Humanities
EM Experimental Medicine
G Genetics
GMX Genomics
GSH Gender, Sex & Health
HPM Health Policy & Systems Management Research
HSI Health Services Evaluation and Interventions Research - B
HSR Health Services Evaluation & Interventions Research - A
IT Immunology and Transplantation
KTE Knowledge Translation & Exchange
M Metabolism
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103
MCC Molecular & Cellular Biology of Cancer
MI Microbiology & Infectious Diseases
MOV Movement & Exercise
MPI Medical Physics & Imaging
NSA Neurosciences - A
NSB Neurosciences - B
NUT Nutrition, Food & Health
PLC Palliative & End of Life Care
POP Public, Community & Population Health - A
PS Pharmaceutical Sciences
PSB Psychosocial, Sociocultural & Behavioural Determinants of Health - A
PSD Psychosocial, Sociocultural and Behavioural Determinants of Health - B
PT Pharmacology & Toxicology
PUB Public, Community and Population Health - B
RS Respiratory System
SDA Social Dimensions in Aging
VVP Virology & Viral Pathogenesis
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104