Résultats de l'outil d'établissement de liens entre partenaires pour la subvention d'équipe : programme sur le virus Zika Canada-Amérique latine-Caraïbes

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L'information est fournie dans la langue dans laquelle le répondant l'a présentée (français ou anglais).

Le tableau ci-dessous contient les renseignements de chercheurs et de personnes désirant échanger de l'information ou établir des collaborations en lien avec la subvention d'équipe : programme sur le virus Zika Canada-Amérique latine-Caraïbes.

Les informations ont été données sur une base volontaire et ne confèrent d’aucune manière aucun avantage dans l’évaluation et le financement des demandes.

Le tableau sera mis à jour chaque mercredi, jusqu'à la date limite de présentation des demandes (2016-07-12). L'information demeurera accessible jusqu'à 2016-07-12.

Coordonnées Domaine d'intérêt Expérience, connaissances, expertise ou contribution en lien avec le programme sur le virus Zika
Vizoso Pinto, Maria Guadalupe
Dr.rer.nat. Biochemist
INSIBIO - CONICET and National University of Tucumán
Telephone: +54-38-1471-1278 and +54-93-8164-97322
guadalupevizoso@yahoo.com
Diagnostics I have experience in classical and recombinatorial cloning, high-trough-put expression and purification of recombinant proteins, serological screening of viral antigens, virus-specific T-cell assays, serological assays and their validation. I also have hand-on experience in protein-protein interactions, reporter assays, Y2H, LuMPIS, BRET, Lumier, confocal microscopy, virus and cell culture, point-of-care tests. I have worked with DNA viruses such as VZV, CMV and HSV and with an RNA-virus, Hepatitis E virus.
Loeb, Mark (en anglais seulement)
Professor
McMaster University

Telephone: 905-525-9140 Ext. 26679
loebm@mcmaster.ca
   
Czub, Markus (en anglais seulement)
Professor
University of Calgary
Telephone: 430-220-4744
m.czub@ucalgary.ca
Pathogenesis We would be able to provide expertise on reverse immunology: i.e. we would screen phage peptides libraries with Zika virus neutralizing antibodies (the latter to be provided to us).
Berthoux, Lionel (en anglais seulement)
Professor / P.I.
Université du Québec à Trois-Rivières
Telephone: 819-376-5011 Ext. 4466
berthoux@uqtr.ca
Pathogenesis I work on antiviral innate immunity, specifically effectors and sensors. I am interested in developing Zika projects in the following directions, working in cells lines that are relevant to in vivo pathogenesis e.g. neurons and placental cells: - Construction of a ZIKV vector system expressing reporter genes such as GFP, in order to perform single-cycle infection experiments with convenient FACS-based readout. - Characterization of sensitivity to various IFN-I, and mechanism of inhibition. - Targeted loss-of-function approach to identify innate sensors (e.g. RIG-I, IFI16, etc.) and innate immune pathways (e.g. NF-kB, AP-1, IRF3) important for ZIKV control. - Loss-of-function genetic screens to identify IRF genes involved in the innate response to ZIKV. The outcome of this project is to establish the potential of IFN-based approaches as an antiviral strategy for ZIKV and other viruses of the same family.
Tremblay, Michel J.
Full professor and scientist
Université Laval and
CHU de Québec-Université Laval research center
michel.j.tremblay@crchudequebec.ulaval.ca
Pathogenesis My laboratory is centered on the study of host and viral factors that can modulate HIV-1 pathogenesis. We developed a unique expertise working with primary human cells (e.g. CD4+ T cells, monocyte-derived macrophages, monocyte-derived dendritic cells, fetal astrocytes, fetal microglial cells, etc) and some unique experimental cell systems (e.g. tonsillar tissue, blood-brain barrier). We are currently performing some preliminary studies using a Zika virus strain isolated from a Canadian traveler returning from Thailand (Am J. Trop Med Hyg 2014, 91: 1035-1038). We produced already some virus stocks in the C6/36 insect cell line and used a plaque assay with Vero cells to titrate our virus preparations. We developed a real-time RT-PCR test to monitor replication of Zika virus.
Houry, Walid
Professor
University of Toronto
Telephone: 416-946-7141
walid.houry@utoronto.ca
Pathogenesis I am a protein biochemist.
Jean, Francois (en anglais seulement)
Scientific Director and
Associate Professor
University of British Columbia
Telephone: 604-822-0256
fjean@mail.ubc.ca
   
Monte-Neto, Rubens (en anglais seulement)
PhD
René Rachou Research Centre -
Oswaldo Cruz Foudation/Fundação
Oswaldo Cruz (Fiocruz Minas)
Telephone: 55-31-97132-7928 or 55-31-3349-7786
rubens.neto@cpqrr.fiocruz.br
Pathogenesis I have a background on molecular biology and pharmacology focused on drug mechanisms of action and resistance in protozoans. I am also familiarized with next generation sequencing and functional genomics applied to genetic reverse approaches. Here is my CV at Brazilian CNPq/Lattes (en anglais seulement) platform.
Sander, Beate
Scientists, Assistant Professor
Public Health Ontario, University of Toronto
Telephone: +1 (647) 260 7425
beate.sander@oahpp.ca
Vector studies - Systematic and integrated vector control approach

Our team (including medical entomologists, epidemiologists, clinicians, mathematical modelers) is interested in both "vector studies" topic areas.

My expertise:
The economic evaluation of public health interventions and programs.
The development and novel application of advanced modelling methods drawing on health economics, decision analysis, and mathematical modelling with a focus on infectious diseases.
The use of administrative, reportable disease and laboratory data for health and economic evaluations.

Most relevant current project: The cost-effectiveness of West Nile virus (WNV) intervention strategies. A computer simulation model (CIHR funded)
The objective of our research is to evaluate the cost-effectiveness of current and future WNV mitigation strategies in Ontario, building on ongoing work in this area. To attain this objective, we propose to develop a computer simulation model, that: (1) predicts mosquito abundance, WNV risk and simulates WNV transmission, (2) estimates health and economic consequences, and (3) determines the comparative effectiveness, economic impact and cost-effectiveness of WNV mitigation strategies.
This work will significantly enhance our understanding of the comparative effectiveness and cost-effectiveness of WNV mitigation strategies and directly support public-health decision making with the aim to achieve the best health outcomes for the resources invested.

França, Patrícia (en anglais seulement)
Doctorate Degree
UFMG; Origen Clinic
Telephone: 55-31-9919-23006
ppf.genetica@yahoo.com
Pathogenesis Molecular Biology experience on virus genotyping and andrology researches.
Troyo, Adriana (en anglais seulement)
Professor
Universidad de Costa Rica
Telephone: 506-2511-8626
adriana.troyo@ucr.ac.cr
Vector studies - Ecological transmission dynamics I work as part of a research team in Medical Entomology. Within of our main research topics, we have investigated and are interested in the biology of Aedes aegypti, Aedes albopictus, and other mosquitoes, mosquito surveillance, transmission and epidemiology of dengue and other arboviruses. Current projects include insecticide resistance in Ae. aegypti, Ae. albopictus and its role as a dengue vector; the next proposal submissions, if awarded, would involve studying the transmission and vectors of zoonotic arboviruses like WNV, EEEV, VEEV, etc. in endemic areas of Costa Rica, as well as the role of different mosquito species and local primates in Zika transmission cycles. Our experience includes collection and surveillance methods, mosquito identification, and molecular detection of host preference and infectious agents. We can work closely with the Vector Control Program of the Ministry of Health. Interests in Zika transmission research may include identification of other possible sylvatic and urban vectos, transmission by Aedes albopictus vs. Aedes aegypti in areas of overlap, co-transmission of Zika and dengue or chikungunya, vector competence studies, among others.
Canario, Julio
Prof
Centro Nacional de Investigaciones en Salud Materno Infantil "Dr. Hugo Mendoza" (CENISMI) (en espagnol seulement)
Telephone: 1-829-643-7635
arturo.canario@gmail.com
   
Rangachari, Manu (en anglais seulement)
Assistant Professor
CHU de Québec; Université Laval
Telephone: 1-418-525-4444 x 46461
manu.rangachari@crchudequebec.ulaval.ca
Pathogenesis
  • cellular immunology; T cell biology
  • models of autoimmunity; specifically, active immunization and T cell adoptive transfer preclinical models of MS
  • rettrovirally-mediated gene transfer
  • flow cytometry
  • mass cytometry (CyTOF)
Hunter, Fiona (en anglais seulement)
Professor
Brock University
fhunter@brocku.ca
Vector studies - Ecological transmission dynamics We are already doing Zika work on mosquitoes and I have a collaboration set up in the Caribbean for field work
Mazon, Talita (en espagnol seulement)
Doctor
Center for Information Technology Renato Archer
Telephone: 55-19-3746-6185
talita.mazon@cti.gov.br
Diagnostics My group have experience on synthesis of ZnO and Au nanostructures, graphene oxide and reduced graphene oxide as well as nanohybrids materials on different substrates, immobilization of antibodies, development of low cost electrochemical biosensor platforms for ovarian cancer and diabetic nephropathy detection. We also have infrastructure to test the electrochemical immunobiosensors. We also have electrical enginners with expertise to develop handle potenciostate. So, we intend to immobilize antibodies specific to Zika on our biosensor platform to develop a simple test that can be use in the point-of-care or governmental health center.
Soares Pontes, Gemilson
PhD
National institute of Amazonian Research
Telephone: 55-92-9825-67382
pontesbm1@gmail.com
Pathogenesis In the past few years I have been carrying out studies related to epidemiology of HTLV and molecular and cellular characteziation o the mucosal antigen sampling system. About thee years ago, I got position at National institute of Amazonian Research and, right here, We are conducting studies related to epidemiology of HTLV, Dengue, Immunopathology of enterobacteria and bioprospection of natural products with antimicrobial activities. This years, we will start at least two studies focusing on surveillance of Zika virus infection in pregnant women residents of amazonas state, Immunopathology involved in Zika virus infection and Vector studies. All studies will be done in collaboration with Oswaldo Cruz institute - FIOcruz.Beyond our great partnership, It would be great establish fruitful international collaboration to fight against this infection, which is spreading over the world.
Cardoso, Jader (en espagnol seulement)
Doctorate
Centro Universitário Lasalle – UNILASALLE
Telephone: 55-51-9231-1872
jader.cardoso@unilasalle.edu.br
Vector studies - Ecological transmission dynamics  
Svoboda, Walfrido (en espagnol seulement)
PhD
Federal University of Latin American Integration (UNILA)
Telephone: 55-45- 8428-0115
walfrido.svoboda@unila.edu.br
Diagnostics Since 2003 I dedicate my professional life to work and research about arboviruses, interest epidemical viral diseases to public health. I wrote my PhD thesis with this theme: "Epizootics surveillance in non-human primates as arboviruses monitoring tool and other interest viruses to public health". In 2005 I was invited by Brazilian Health Ministry to develop the first "Epizootics Surveillance Guideline to Non-Human Primates, in order to improve the surveillance and control of yellow fever in Brazil. In 2007 I had invited by the Research Institute for Health Sciences (IICS) of the National University of Asunción (UNA) to provide consulting / technical assistance and training health professionals from Paraguay, in order to improve the epizootics surveillance non-human primates for research and control of yellow fever in Paraguay. Also, I have a consistent scientific production with research related to the investigation of arboviruses of interest in public health. Currently I have coordinated a research project in partnership with the Federal University of Paraná (UFPR), developing methods for Dengue, Chikungunya and Zika virus diagnoses, and participate as a collaborator in another aimed at the detection of these viruses in vectors and vertebrate reservoirs.
Cordo, Sandra
PhD
Buenos Aires University
scordo@qb.fcen.uba.ar
   
Ogusuku, Elena
Biologist
General Directorate of Environmental Health - Ministry of Health of Peru
Telephone:  05-19-9800-6636 
elenaoa2013@gmail.com
Vector studies - Systematic and integrated vector control approach I'm biologist entomologist, working in the vector control unit of the Ministry of Health. I have 15 years of experience on entomology surveillance and integrated vector control.
Even the chemical control is the main vector control strategy, I have strong interest to develop community based prevention tools to add to. As an example, I have develop a project study to develop the rice intermittent irrigation system for the malaria vector control, based on community participation, which now is taking by the Ministry of Agriculture as an agriculture innovation.
Since 10 years ago, the most part of the budget for national vector control is spent on Aedes aegypti control, but year to year is spread in more areas. Now we are the challenge to deal with the high level on resistance to several types of insecticides. In this context, we need to develop alternative ways to prevent the dispersion of Zika outbreak and continuous spread of Aedes aegypti.
Prophiro, Josiane (en espagnol seulement)
PhD in Health Sciences
UNISUL - Universidade do Sul de Santa Catarina (University of Southern Santa Catarina) and UFCSPA - Universidade Federal de Ciências da Saúde de Porto Alegre (Federal University of Health Sciences of Porto Alegre)
Telephone: 55-48-9109-3458
josiane.prophiro@hotmail.com
Vector studies - Systematic and integrated vector control approach I work with bio-ecology and vector control and have interest in both areas of vector studies. I'm interested in control, bio-ecology and vector immunology. This is my CV at Brazilian CNPq / Lattes platform.
Moura, Patricia (en espagnol seulement)
PhD
Universidade de Pernambuco
Telephone: 55-81-3241-4952
patricia.moura@upe.br
Pathogenesis Associate Professor at University of Pernambuco. Graduated in Biomedicine (Federal University of Pernambuco, 1990) with stage at the University of Georgia (UGA) during his graduation and did his Masters in Microbiology from UFRJ (1994), where he developed a kit for the diagnosis of visceral leishmaniasis, now marketed by biogène .Doctorate in Biological Sciences in the field of Biotechnology, where he studied the binding lectin mannose and its role in infection by dengue virus in collaboration with Dr. Claire Kubelka the Instituto Oswaldo Cruz (IOC), Rio de Janeiro and with Dr . Nigel Klein of the Institute of Child Health, University College London and Dr. and Margot Anders University of Melbourne. Post-doctoral title was obtained by Aix-Marseille Université studying epigenetic mechanisms in the progression of liver disease caused by hepatitis C virus (HCV).
Vasconcelos,  Luydson (en espagnol seulement)
PhD
Centro de Pesquisas Aggeu Magalhães - FIOCRUZ-RECIFE-PE
Telephone: 55-81-9645-2018
luydson.vasconcelos@cpqam.fiocruz.br
Pathogenesis Degree in Biological-Bachelor Science (2005) from the University of Pernambuco, Master of Health Sciences - FCM / UPE (2009) and Doctorate in Biotechnology in Health (2013) by RENORBIO program with experience in Medical Genetics area and Molecular Biology Applied to health, with emphasis in Immunogenetics and Molecular Diagnostics of Infectious diseases, mainly in the identification of genetic polymorphisms of immunity associated with susceptibility to infection or progression of diseases such as hepatitis B and C, sickle cell anemia, leprosy, dengue, HIV and HTLV. It has experience in laboratory management area in Molecular Diagnostics, using real-time PCR to determine viral load and genotyping. Developed Postdoctoral at Aix-Marseille University II - France, studying patients with HCV and the implication of genes and pathways involved in the development of fibrosis using gene expression approach (transcriptome), DNA methylation (metiloma) and SNP analysis of genes involved in the process of liver fibrosis is currently a researcher in public health at the Center for Aggeu Magalhaes-RECIFE-Fiocruz-PE.
Ayoade, Femi
Senior Lecturer, Sub-Dean College of Natural Sciences
Redeemer's University, Ede, Osun State, Nigeria
Google Scholars citations
Telephone: 23-47-0696-33494
ayoadef@run.edu.ng
Vector studies - Systematic and integrated vector control approach My experience in entomological research into the endocrinological and genetical regulation of metamorphism is relevant to vector control in Zika Virus Research. In previous published works we have demonstrated the presence genetic variability in wing dimorphism in the brown planthopper, Nilaparvata lugens in the field populations showing different responses to density and generated genetically genuine strains predominantly showing specific wing-form and body-color in broad range of density.
ln this research, we first used the two strains showing specific wing-from by topically applying juvenile hormone or anti-juvenile hormone, precocene to the nymphs in various developmental stages to know the effect of them on wing-from, ovarian development and metamorphosis. We found that juvenile hormone induced brachyptery in the macropterous strain and enhanced its ovarian development, while prococene induced macroptery in the brachypterous strain and retarded its ovarian development, when applied in specific developmental stage. The results strongly supported that life history characteristics such as nymphal period, adult longevity, preoviposition period, fecundity, egg period were demonstrated to differ among four strains, suggesting the involvement of the genes for wing-form and body color expression also to control these life history characteristics, possibly through regulation of the synthetic activity of juvenile hormone by corpora allata.
Jorge, Acosta-Reyes
MD, MSc in Clinical Sciences
Universidad del Norte (en espagnol seulement)
Telephone: 57-30-0319-0018
acostajl@uninorte.edu.co
Pathogenesis

In Barranquilla Colombia, our research´s group have been working in arbovirosis. In the last year our focus is Zika. We work in conjunction with the Department of Health of Barranquilla, in surveillance, monitoring and reporting of new cases of Zika virus infection and complications (microcephaly, Guillain-Barre Syndrome and others complications). Our university have a team of clinical, infectologists, virologists, immunologists, epidemiologists and public health experts that supports these type of research.

We recently published an article about fatal cases with dengue and chikungunya virus coinfection.

Fahl, Gabriela (en portugais seulement)
Master
Universidade Federal de Goias
Telephone: 55-62-9811-88999
gabi.fahl@hotmail.com
Vector studies - Ecological transmission dynamics Hello! I'm a geographer and got into a PhD programme to study the linkage between Aedes aegypti and geographical factors, such as climate, economic situation and social status. I'm planning on collecting all the information about the region with most incidence of zika and dengue in Brazil and correlate with these factors. I do belive by the time I finish modelling the data, I'll be able to build a scale of risk suitable to predict how changing the factor will reflect on the incidence of the disease, and so help public policy to improve the assistence to the ones in danger. With some more time, I can also include other regions and improve the mathematical model to include more variables and test it on more locations.
Kaushic, Charu
Professor
McMaster University
Telephone: 905-525-9140 X 22988
kaushic@mcmaster.ca
Pathogenesis Animal modeling of viral infections, in vitro modeling of viral-host interactions, pregnancy models in mice, reproductive biology, mucosal infections and immune responses.
Pimenta, Paulo (en portugais seulement), PhD
Centro De Presquisas Rene Rachou - Fiocruz
ResearchGate profile
Telephone: 55-31-9820-20634
pfppimenta@gmail.com
Vector studies - Ecological transmission dynamics My main interest is to develop studies in the 3rd item: Vector Studies
  1. the ecological transmission dynamics of Zika virus;
  2. the assessment of systematic and integrated vector control approach involving communities complemented with the evaluation of new technologies.
I am a Brazilian senior researcher working at FIOCRUZ in Belo Horizonte and Manaus, two ecologically distinct cities but both endemic for Dengue and now invaded by Zika. In Manaus, I am working in a hospital specialized in assisting Malaria, Dengue and Zika patients. I have experience in working with Dengue vectors studying competence, transmission dynamics and xenomonitoring (as a new tool to early detection and control DENV circulation). We already have good preliminary results with Zika: (a) 2 distinct Brazilian ZIKV strains growing in cell cultures (and other 2 frozen strains); (b) successfully infecting colonized and field-caught Ae. aegypti and Ae. albopictus with ZIKV (and checking other mosquito species), and (c) using Real-time PCR for detecting ZIKV. We have good preliminary results demonstrating our ability to pursue the aims that we intent to propose. We are open to new ideas and to go further with Canadian partners to study develop ZIKA vector biology, but also to investigate other interesting aspects.
Silva, Italo (en portugais seulement)
Master Degree Student
Universidade Federal de Vicosa
Telephone: 55-31-3899-2559
italo.poly@ufv.br
   
Sousa, Klayton
Ph.D.
Federal University of Rio Grande do Norte / Brazil
Telephone: 55-34- 9811-00633
ftklayton@hotmail.com
Pathogenesis I am conducting an epidemiological investigation into the recent outbreak of infection ZIKV and its relationship to the observed increase in cases of microcephaly in Brazil. My aim is to study the surveillance, promotion and the control of the microcephaly to public health of children in all health care levels. In order to arrange the services with programmed actions of comprehensive health care of the development child, contributing to the access of this population to different activities and health actions minimizing the losses social, collective and family.
Quentin, Emmanuelle
Ph.D.
Instituto Nacional de Investigación en Salud Pública (Ecuador)
Telephone: 593-(0)98-149-6522
emmanuelle.quentin@gmail.com
Vector studies - Ecological transmission dynamics Graduated in mathematics-informatics, water science and remote sensing in Canada, I am working in Ecuador in its National Health Institute collaborating since 2 years to a scientific research on zika virus vector, Aedes aegypti, focusing on the spatio-temporal analysis and modelling of its distribution.
Dumais, Nancy
Full Professor
Université de Sherbrooke
Telephone:  8-19-821-8000
   
Skeete, Gary
Research Doctor
University of Toronto
Telephone: 905-497-2058
Garyskeete@hotmail.com
Diagnostics Chikungunya and now ZIKA in Barbados Facebook group
Please refer to past research on this site postings and comments submitted.
Pando-Robles, Victoria
Professor
National Public Health Institute of Mexico
Telephone: 51-777-3293000
victoria.pando@insp.mx
Vector studies - Ecological transmission dynamics Our research interest are focused to understand the interactions between dengue virus and host cell, by comprehension of dengue pathogenesis mechanism in the both host, human and insect. To date, I am interested to start studies in zika virus. Particulary, in dynamics of zika transmission. I would like to participate in a research group that have experience in virus vector transmission. My idea is collect mosquitos from different parts of Mexico, and in laboratory conditions evaluated the capacity of mosquitoes to infection with zika, to dissemination of virus in the vector body and the vectorial competence of this mosquito to transmit zika virus.
My institute is localized in Cuernavaca, Morelos an endemic región for dengue and I have access to samples from Tapachula, Chiapas, a región endemic for dengue, zika and chikungunya viruses.
Peña Sepulveda, Emiliana del Carmen
Medical doctor, expertise in public health, epidemiology Masters
Ministerio de Salud Publica, Universidad Autonoma de Santo Domingo
Telephone: 1-809-861-0758
emiliana.pena@sespas.gov.do ; epenasepulveda@gmail.com
Vector studies - Systematic and integrated vector control approach We currently have by conducting assessments of results implemented comprehensive interventions for the control and prevention of disease virus Zica.
Peguero,  Matilde
Doctora
Ministerio de Salud Publica
Telephone: 8-29-542-7011
matildepeguero@gmail.com
Vector studies - Ecological transmission dynamics Actually I'm working as investigation coordinator of General Direction of Epidemiology in Dominican Republic, and has been involved in so many activity in context of epidemic in DR
Franz-Odendaal, Tamara
Professor
Mount Saint Vincent University
Telephone: 902-457-6140
tamara.franz-odendaal@msvu.ca
Pathogenesis I am a developmental biology working on neural crest cells for the last 12 years. Specifically I study neural crest derived bones of the skull. The calvariae (skull roof) is of particular interest. we use morphometrics to study the shapes of bones as well as molecular techniques to understand how these cells make bone.
Colome Hidalgo, Manuel
Epidemiologist-Bioethicts
Centro de Investigacion en Salud Hospital Dr Hugo Mendoza
Telephone: 809-568-8222
manuel.colome@hhm.gob.do
Pathogenesis We would like to work on the relationship of Zika virus infection and the pathogenesis of Guillian Barre syndrome on our pediatric hospital on the Dominican Republic.
Expertise on pediatric diseases.
Clinical expertise of Arbovirus diseases.
Herrera Morban, Demian Arturo (en anglais seulement)
Pediatrician
Centro de Investigacion en Salud Hospital Dr Hugo Mendoza
herreramorbanmd@gmail.com
Pathogenesis We would like to work on the relationship of Zika virus infection and the pathogenesis of Guillian Barre syndrome on our pediatric hospital on the Dominican Republic.
Expertise on pediatric diseases.
Clinical expertise of Arbovirus diseases.
Pardee, Keith (en anglais seulement)
Assistant Professor
University of Toronto
Telephone: 416-946-5289
keith.pardee@utoronto.ca
Diagnostics

Our proposed project is focused on the deployment of a new low cost Zika virus diagnostics platform to the field in Latin America and the Caribbean. We recently published the diagnostic assay and workflow in the journal Cell (en anglais seulement) where we demonstrated detection of the Zika virus RNA genome at clinically relevant concentrations (1 – 3 femtomolar). Our combined biomolecular tools can detect global strains of the Zika virus (Asian-, African- and American-lineages) as well as distinguish between them, and using our electronic reader we can provide quantitative, lab-grade capabilities in a portable format. We further demonstrated our technology on active virus, as well as showed that we can detect the virus directly from infected plasma without purification or concentration of the virus.

We now seek to further develop the field readiness of the technology platform by creating a low cost device that can prepare patient samples and run the Zika diagnostic assay in only one step for users. As part of this, we are seeking collaborators in the regions affected by the Zika virus and who have experience with the outbreak. The goal of this partnership is evaluate the diagnostic technology under field conditions with patient samples.

Cavalcanti, Socrates (en anglais seulement)
Doctor
Federal University of Sergipe, Brazil
Telephone: 55-79-99117-2998
mailto:socratescavalcanti@yahoo.com.br
Vector studies - Systematic and integrated vector control approach Our laboratories study the synthesis of larvicidal compounds against Aedes aegypti (Zika vector). Promising compounds are pushed forward to formulation, residual effect tests and field evaluation.
Cattapan, Alana (en anglais seulement)
CIHR Postdoctoral Fellow
Dalhousie University
Telephone: 902-494-2936
alana.cattapan@dal.ca
Ethics, legal, social research related to women's reproductive health and autonomy.
Visanuvimol, David
Application Specialist, Infectious Disease
DNA Genotek Inc.
Telephone: 613-723-5757 ext. 244
david.visanuvimol@dnagenotek.com
Diagnostics I am trained in molecular genetics and currently working for a for-profit, biotech company. We have technology that can stabilize viral RNA in 1ml of saliva at ambient temperature for 3 weeks. We are looking for partners both in Canada and in LAC to validate and implement the saliva stabilization kits and urine RNA stabilization prototypes for differential diagnostic of Zika, Dengue, and Chikungunya infections.
Rufalco Moutinho, Paulo
PhD
Faculdade de Saúde Pública - Universidade de São Paulo
paulorufalco@usp.br
Vector studies - Ecological transmission dynamics Ecology and epidemiology field research on malaria vectors on rural settlement of Amazon Basin and dengue fever vectors on urban landscape of middletown city on State of São Paulo (Brazil). Experience with environment and molecular analysis and vectorial importance of the mosquitoes biodiversity and emergence of infectious disease.
Montenegro, Carlos
University Centre UNZAC.
San Carlos University of Guatemala
Telephone: 502-55384931

carlosmontenegroquinonez@gmail.com
Vector studies - Systematic and integrated vector control approach

I have been involved in the development, management and implementation of projects in areas related to public health, integrated vector control management and neglected tropical diseases. During my bachelor studies in biology and subsequent professional life, I participated as an associated researcher for the Laboratory of Applied Entomology and Parasitology, during this time, I co-developed and implemented projects for the control of the Dengue vector and the study of the Paragonimus parasite in Guatemala. In addition, I also participated in an epidemiological study of dengue in Guatemala.

During my master studies in International Health, in the institute of public health of the University of Heidelberg, I participated in an International project involving dengue. The Dengue Tools consortium implemented the project. This project included institutions from Germany, Sweden, France, Thailand, Sri Lanka, among others. I participated in the study of the bionomics of the Aedes mosquitos in Sri Lanka.

The research center of the San Carlos University, in which I am affiliated now, has the strong will and expertise to implement a national project for the control of Zika virus in collaboration with international and other national institutions, being a national priority and a disease with urgent need of attention.

Garcia Aguirre, Laura
MD. PhD. Clinical Pathologist
Centro Hospitalario Pereira Rossell (en espagnol seulement)
Telephone: 598-99618748
lauraga@adinet.com.uy
Diagnostics I am Head of the Molecular Biology Laboratory at the Centro Hospitalario Pereira Rossell, that includes the Children´s Hospital and the Women´s Hospital. We have the biggest maternity of the country and we assist both hospitals (Children´s and Women´s) were all Uruguayan pediatricians and gynecologist are trained. We deal with clinical samples and we work with the Ministry of Health in epidemiology aspects of our work. We are preparing for Zika entrance to our country and also to dengue virus infection diagnosis.
Neves, Adriana
Post doctor
Federal University of Goias (UFG)
Telephone: 55-64-981465536 (cell phone),
or 55-64-3441-5324 (UFG)
neves.af@gmail.com
Diagnostics Molecular biology
Molecular markers
RT-PCR (conventional and Real Time)
Selex
Selection and characterization of aptamers
Cell biology study/aptamers transfection
Gene expression
Polymorphism
DNA and RNA study
Other Molecular techniques such as electrophoresis, dot blot, PCR-RFLP, sequencing
Test of aptamers by using FRET
In silico analysis: probe design, primers design, secondary structure of oligonucleotides, hybridization
Some publications:
NEVES, A. F.; CNOSSEN, E. J. N. ; MARANGONI, Karina ; FUJIMURA, Patrícia T ; SILVA, A. G. ; SANTOS, Fabiana ; YOKOSAWA, J. ; GOULART, Luiz Ricardo . Selection and characterization of RNA aptamers targeting the genomic 5'-UTR in the dengue virus. San Francisco, CA, USA. Proceedings of 3rd International Conference on Medicinal Chemistry & Computer Aided Drug Designing: Omics Group Conferences, 2014. v. 4. p. 85-85. Prostate-specific RNA aptamer: promising nucleic acid antibody-like cancer detection. Marangoni K, Neves AF, Rocha RM, Faria PR, Alves PT, Souza AG, Fujimura PT, Santos FA, Araújo TG, Ward LS, Goulart LR. Prostate cancer antigen 3 (PCA3) RNA detection in blood and tissue samples for prostate cancer diagnosis. Neves AF, Dias-Oliveira JD, Araújo TG, Marangoni K, Goulart LR. Clin Chem Lab Med. 2013 Apr;51(4):881-7. doi: 10.1515/cclm-2012-0392.
Francis, Sheena
University of the West Indies, Mona Jamaica
Telephone: 352-497-0218
sheena.francis02@uwimona.edu.jm
Vector studies - Systematic and integrated vector control approach Our lab normally analyses natural products effect on human metabolizing enzymes, eg. CYP450. Recently we started analyzing natural extracts from Jamaican endemic plants against mosquitoes CYP450, and found some compounds to be very active (in press). We have also conducted studies to determine the efficacy of pesticides currently being used in Jamaica (in press). We are hoping to continue work along this line in order to tract and manage insecticide resistance also to test novel compounds for their insecticidal properties.
Hunter, Fiona
Professor
Brock University
fhunter@brocku.ca
Vector studies - Ecological transmission dynamics We are already doing Zika work on mosquitoes and I have a collaboration set up in the Caribbean for field work.
Sierra, Beatriz
Full Professor and Scientist
Pedro Kourí Institute of Tropical Medicine (IPK) PAHO/WHO Collaborating Center for the Study of Dengue and its Vector
Telephone: 53-7255-3559
siebet@ipk.sld.cu
Pathogenesis Our team is focused on the study of host immunological and genetic factors that could modulate flavivirus pathogenesis, in particular, Dengue and Zika virus.
Guzman, María Guadalupe
Head of the Centre for Research, Diagnostic and Reference of the Institute for Tropical Medicine “Pedro Kourí”
Institute of Tropical Medicine "Pedro Kourí" (IPK)
Telephone: 53-7255-3556
lupe@ipk.sld.cu
Diagnostics Our group is a WHO/PAHO Collaborating Center for Dengue and its Vector and it currently coordinates the Dengue Laboratory Network of the Americas (RELDA/PAHO). We had received grants from International funding resources as partners of International projects. We are responsible of the National Surveillance of Dengue, Zika and Chinkungunya and other Arboviruses in Cuba. We have skills on viral isolation, PRNT assay, virological and molecular characterization of Dengue strains. We have an animal house and a tissue culture unit with a cell bank and a serum bank. Our research experience has been focused in molecular epidemiology studies of Dengue virus, evaluation of the performance of IVD kits for serological diagnosis of Dengue and Chikungunya, development of an in house IgM capture ELISA for Dengue diagnosis, studies of host immunological and genetic factors that could modulate Flaviviruses pathogenesis, in particular, Dengue and Zika virus. Moreover, we had obtained a recombinant dengue antigen as an immunogen, have evaluated the Dengue immune response in animal models (mice and monkeys) immunized with recombinants proteins. Our main interest to the Canada-Latin America and Caribbean Zika Virus Research Program would be in the research areas of pathogenesis studies and the improvement of Zika diagnosis.
Espinal, Carlos
Director Global Health Florida International
University Miami Florida
Florida International Univeristy
Global Health Consortium (en anglais seulement)
Telephone: 703-203-5862
caespina@fiu.edu
Diagnostics Director of Global Health at FIU, expertise on dengue, vaccination, public health, malaria and other tropical diseases. Disease surveillance, member of the Several infectious and tropical diseases scientific associations.
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