CIHR HIV/AIDS Research Advisory Committee (CHARAC) – Biographies

Keith Fowke, Chair
Head
Department of Medical Microbiology
University of Manitoba

Dr. Fowke received his PhD in Medical Microbiology (1995) from the University of Manitoba (UM) and did a postdoctoral fellowship at the National Institutes of Health in Bethesda, Maryland (1995-1999). In 1999 he was recruited to the UM’s Department of Medical Microbiology and is currently a full professor and the Head of the Department. He is also cross-appointed with the Department of Community Health Science (UM) and the University of Nairobi’s Department of Medical Microbiology. Dr. Fowke’s laboratory focuses on defining cellular immune mechanisms for the control of, and resistance to, HIV infection. Currently the lab is focused on preventing HIV infections by inducing immune quiescence using anti-inflammatory agents and defining the impact of sex work on the immune response in the female genital tract. Dr. Fowke has a particular interest in training young investigators in multi-disciplinary research and has been involved in a number of workshops and international training programs.


Marni Amirault
Community-Based Research Manager
Aboriginal HIV and AIDS Community-Based Research Collaborative Centre (AHA Centre)

Marni Amirault is of Acadian and English/Irish descent. She has her Master of Arts in cultural / visual anthropology from the University of Alberta where her research focus was on Aboriginal media making. Marni has worked with and lived in several First Nations, Inuit and Métis communities in Canada since 2001 and has been involved in the field of Aboriginal sexual health since 2009. She currently holds the position of Community-Based Research Manager (KT) with the Aboriginal HIV and AIDS Community-Based Research Collaborative Centre (AHA Centre), a project of the Canadian Aboriginal AIDS Network (CAAN). In this role, she works collaboratively with academic and community researchers and organizations to build and maintain relationships, offer support in all stages of Aboriginal HIV and AIDS community-based research and to promote research. She is co-editor for the Canadian Journal of Aboriginal Community-Based HIV/AIDS Research (CJACBR), co-chair of the National Aboriginal Research Advisory Committee (NARAC) with CAAN, a member of the AIRN Blended Leadership Committee and a team member on several research grants.


Chris Archibald
Director, Surveillance and Epidemiology Division
Centre for Communicable Diseases and Infection Control
Public Health Agency of Canada

Chris Archibald has a medical degree from McGill University and specialist certification in public health and preventive medicine from the University of British Columbia. For the past 15 years, he has been Director of the division responsible for national HIV/AIDS epidemiology and surveillance at the Public Health Agency of Canada; for the past 5 years, he has also been responsible for national surveillance of other sexually transmitted infections, TB, and hepatitis. In addition to his national responsibilities, Dr. Archibald has worked on international surveillance and research projects in Colombia, the Caribbean, eastern Europe, and south Asia in support of the Agency’s Partnership Agreement with UNAIDS and in association with the World Health Organization, the Pan American Health Organization, and Canadian international development work.


Vera Caine
Professor, Faculty of Nursing
University of Alberta

Dr. Vera Caine is a Professor and CIHR New Investigator in the Faculty of Nursing at the University of Alberta. Her community based research focuses primarily on the relationship between the social determinants of health and people living with HIV. Vera has received CIHR and SSHRC funding. She is interested in the relational and ethical aspects of narrative inquiry, as well as community based and participatory research methods and methodologies.


Andrés Finzi
Assistant Professor and Canada Research Chair on Retroviral Entry
Centre de recherche de CHUM (CRCHUM)
Université de Montréal

Dr. Andrés Finzi is a Canada Research Chair on Retroviral Entry. Dr Finzi was recruited in September 2011 by the University of Montreal and the CRCHUM Institute to expand his research program on HIV-1 envelope glycoproteins conformational changes and new strategies to eliminate HIV-1-infected cells.


Trevor Hart
Professor
Department of Psychology
Ryerson University

Dr. Trevor Hart is the Director of the HIV Prevention Lab. He holds a Research Chair in Gay and Bisexual Men’s Health from the Ontario HIV Treatment Network. Dr. Hart is currently conducting four studies, three of which are intervention/therapy studies to prevent HIV sexual transmission and to promote sexual and mental health. Dr. Hart also holds a CIHR Team Grant in Boys’ and Men’s Health, which involves a cross-sectional study of prevalent and recent infections of HIV and other sexually transmitted and blood-borne infections (STBBIs) among 2,100 gay, bisexual, and other men who have sex with men in Vancouver, Toronto, and Montreal.

Dr. Hart received his doctorate in clinical psychology from Temple University. After graduate school, he completed a post-doctoral fellowship at Emory University School of Medicine, through which he received training at the Division of HIV/AIDS Prevention of the U.S. Centers for Disease Control and Prevention. He then worked for four years as an Assistant Professor at York University before joining the Department of Psychology at Ryerson in 2007. He has received several awards for his advancements to research and clinical work, including membership in the College of New Scholars, Arts, and Scientists of the Royal Society of Canada, Fellow of the Association for Behavioral and Cognitive Therapies (ABCT), and a recent Ryerson University Social Innovation and Action Research Award.


Alexandra King
General Internist with HIV/HCV focus
Lu'ma Medical Centre

Dr. Alexandra King, MD, FRCPC, is a member of the Nipissing First Nation (Ontario). She is an Internal Medicine Specialist with a focus on HIV/AIDS, hepatitis C (HCV) and HIV/HCV coinfections, for which First Nations, Inuit, and Métis bear a disproportionate burden. She works at the Lu’ma Medical Centre(Vancouver), an Indigenous health and wellness centre providing excellence in holistic care using both Indigenous and Western healing approaches. She also co-leads a collaborative project to provide Williams Lake, B.C., and surrounding communities with a shared model of hepatitis C care.

As a First Nation researcher, Alexandra is a Principal Investigator on various CIHR research grants related to Indigenous people and HIV, HCV and co-infections. Other research interests include Indigenous wellness and Indigenous research ethics. She works in community-based research centered on Indigenous ancestral wisdom and lived experience; similarly, she develops intervention research that is grounded in Indigenous epistemology, culture and wellness. Indigenous research philosophies and methodologies, as well as Two-Eyed Seeing, are combined to produce innovation and excellence in the research processes and outcomes, and peer-based navigation, support and research; land-based cultural retreats; and land-based research.

Alexandra has co-developed and co-teaches Indigenous health courses at Simon Fraser University. She serves on many local and national initiatives, including the CanHepC: the Canadian National Aboriginal Working Group on HIV & AIDS, the Interagency Coalition on AIDS and Development, and the CIHR Canadian HIV Trials Network(CTN) Working Group for Health for People Who Use Drugs(co-lead).


Joanne Lindsay
Board member
Ontario AIDS Network (OAN)

A women’s equality advocate experienced in community development, community-based training, education and research, Joanne’s community work includes advocating for women’s skills training, bridging and literacy programs, while managing various learning programs in Toronto, Ontario. Incorporating a gender lens into labour market research and policy development, Joanne was the Women’s Representative to the Canadian Labour Force Development Board (CLFDB). Prior to this, Joanne completed a research study tour of worker co-operatives in eastern and southern Africa (Tanzania, Zambia, Zimbabwe, Kenya), travelling the region from a base at the Co-operative College of Tanzania, Moshi.

HIV research became a focus in her work in 2008. She is a board member of the Ontario AIDS Network (OAN), representing Toronto, and recently completed a four-year term on the Board of the Ontario HIV Treatment Network (OHTN). Joanne has a Master’s degree in Community Development/Action Research (Environmental Studies, York University), an Honours BA in Geography (University of Alberta) and is currently a Community Investigator with CANOC (Canadian HIV Observational Cohort Collaboration), researching the link between HIV, HPV and cancer risks for HIV+ women as a member of CANOC’s Cancer Working Group. Her research focuses on women’s access to prevention, screening and treatment of HPV-related cancers, while using evidence to help HIV+ women understand, and act on, their cancer risks. She works out of the Centre for Urban Health Solutions (C-UHS) of St. Michael’s Hospital, Toronto.


David Moore
Research Scientist
BC Centre for Excellence in HIV/AIDS
St. Paul's Hospital

Dr. David M. Moore is a public health physician and Research Scientist at the BC Centre for Excellence in HIV/AIDS, and an Associate Professor in the Department of Medicine, Division of AIDS, at the University of British Columbia. He is also the Physician Lead of the HIV Program at the BC Centre for Disease Control. He has been conducting health service and population health research in HIV since 2004 and is an author or co-author of approximately 90 research publications.

Dr. Moore conducts research related to HIV risk behaviour among MSM in BC. Known as the Momentum Study, it uses a novel approach to recruit study participants known as respondent-driven sampling. He is also a co-PI for a Team Grant which is implementing a study of HIV and MSM in Toronto, Montreal and Vancouver known as the Engage Study.

In addition, he is currently the PI of a CIHR-funded cohort study in Uganda which is examining the outcomes of HIV-infected individuals who have been receiving HIV treatment for more than four years without the laboratory monitoring which usually accompanies the provision of HIV treatment in industrialized countries. Dr. Moore was also a site PI of the Canada-Africa HIV Prevention Trials Network, a research capacity-building grant which involves HIV research teams in Canada, South Africa, Kenya and Uganda. He and his wife created a Canadian foundation to support a home for orphaned children in Kenya in 2004 and continue to provide ongoing support to this organization.


Mario Ostrowski
Professor of Medicine, Immunology and Pathology and Laboratory Medicine
University of Toronto

Mario Ostrowski is full professor of Medicine, Immunology and pathobiology and lab medicine at University of Toronto and also is a consultant infectious diseases clinician at St. Michael's Hospital in Toronto, Canada. His interests include studies on T cell immunoregulation in HIV and HCV infection, molecular adjuvants for vaccination, pDC-virus interactions, and the role of endogenous retroviruses in HIV infection.


Marc Ouellette
Scientific Director
Institute of Infection and Immunity
Canadian Institutes of Health Research

Dr. Ouellette obtained his Bachelor of Science (Honours) in Biochemistry at Ottawa University and received his PhD at Laval University on antibiotic resistance in bacteria. His postdoctoral studies were done under the mentorship of Pr. Piet Borst of the Netherlands Cancer Institute in Amsterdam, where he further developed his expertise in antimicrobial resistance studying protozoan parasites.

In 1990 he joined the Centre de Recherche en Infectiologie, of Laval University as an Assistant professor and is now full professor. Dr. Ouellette's research is focused on antimicrobial resistance where he has made seminal discoveries on resistance mechanism in protozoan parasites. More recently he has implemented proteomic and DNA microarray strategies to study antimicrobial resistance in the parasite Leishmania and the bacteria Streptococcus pneumoniae.

Dr. Ouellette has received numerous awards for his work including a New Investigator Award in Molecular Parasitology from the Burroughs Wellcome Fund, a MRC Scientist Award, a Scholar Award in Molecular Parasitology of the Burroughs Wellcome Fund, and a Tier 1 Canada Research Chair in Antimicrobial Resistance. He is a Fellow of the Royal Society of Canada and of the Canadian Academy of Health Sciences. He has served on numerous panels of national and international granting agencies and is a strong supporter of scientific exchanges with developing countries.


Tim Rogers
Director of Knowledge Exchange
CATIE

Tim Rogers is the Director of Knowledge Exchange at CATIE. He has been involved with CATIE for almost 20 years, first as a volunteer and then a staff member. During this time, he has watched CATIE grow from a local organization working in HIV treatment to a national knowledge exchange organization working in all aspects of HIV and HCV prevention, care, treatment and support.


Jean-Pierre Routy
Professor, Department of Medicine and Experimental Medicine
McGill University

Jean-Pierre Routy has dedicated the last two decades bringing science and treatment innovation to help combat the health challenges of AIDS and cancer care. His fight in health and AIDS related malignancies has led him to obtain the McGill University Louis Lowenstein Chair in Hematology & Oncology. He is an attending physician in the Division of Hematology and Chronic Viral Illness Service at the Royal Victoria Hospital and Professor in the department of Medicine and Experimental Medicine at McGill University, Montreal Canada.

After completing his training in Medicine and Hematology-Oncology at University Aix-Marseille in 1986, he obtained a Postdoctoral Research Fellow Award from the Canadian HIV Trials Network (CTN) and became Assistant Professor in the Department of Medicine at the University of Montreal. In 1994, Dr. Routy joined McGill University and was promoted Associate Professor and co-director of the Flow Cytometry Laboratory at the Royal Victoria Hospital.

As an FRSQ Clinician-Scientist, he was able to implement the Montreal Primary HIV-Infection cohort, which generated important findings in HIV pathogenesis and drug resistance. His achievements have led Dr. Routy to become the National Co-Director of the Immunotherapy and Vaccine Core at the Canadian Health Research Institutes for HIV Trials Network. Since 2011, he co-chairs the Eradication Clinical Working Group for the International AIDS Society. Dr. Routy is also a member of the HIV/AIDS Research Advisory Committee for the Federal Government of Canada.

Dr Routy has authored or co-authored over 250 peer-reviewed publications including articles in journals such as: New England Journal of Medicine, The Lancet, Nature Medicine, Blood and AIDS, he also authored a book entitled “What AIDS has changed” which he has won a literary award from the Ottawa Saint Paul University.


Cécile Tremblay
Professor
Department of Microbiology, Immunology, and Infectious Diseases
University of Montreal

Cécile Tremblay is an infectious diseases/medical microbiologist specialist at the University of Montreal/Pfizer Chair in Translational HIV Research. She is full professor in the Department of Microbiology, Immunology, and Infectious Diseases at the University of Montreal and a researcher at the University of Montreal Hospital Research Centre (CRCHUM). She obtained her M.D. at the University of Montreal in 1992. She did her residency in medical microbiology and infectious diseases at the University of Montreal and was certified by the Royal College of Physician of Canada in 1997. She then pursued a post-doctoral fellowship in HIV research at Massachusetts General Hospital, Harvard Medical School. She came back to Montreal in 2001, where she developed a research program focused on studying the virological determinants of HIV disease progression as well as molecular pathways involved in drug resistance. She is the founder and director of a pan-Canadian cohort of HIV-infected subjects with slow disease progression, which is a collaborative effort by Canadian researchers to better understand HIV immunopathology. She is also coordinating a research initiative on premature aging and cardiovascular disease in HIV in Canada. From 2012 to 2015, she served as Director of the Laboratoire de Santé Publique du Québec (Quebec Public Health Laboratory). During her mandate, she developed a research program on HIV epidemiology in Québec and was responsible for the coordination of the laboratory response to biological threats and emerging infectious diseases.

She has been involved in several initiatives on HIV prevention both in West Africa as well as in Canada. She is the Canadian principal investigator for the Ipergay trial which demonstrated the efficacy of pre-exposure prophylaxis (PrEP) in a population of gay men. She has set up a prospective cohort of MSM to study the uptake of PrEP and its impact on HIV incidence. She is piloting several projects on HIV prevention in various key populations such as people from HIV endemic countries living in Quebec and vulnerable indigenous populations.

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