The Canadian Longitudinal Study on Aging (CLSA) is one of CIHR's Major Strategic Initiatives. Its development was championed by the Institute of Aging. The fundamental goal of this initiative is to mobilize experts in the community to generate a longitudinal research platform based on a protocol developed through expert advice and three international peer reviews.
The CLSA is a large, national, long-term study that will follow approximately 50,000 Canadian men and women between the ages of 45 and 85 for a period of at least 20 years. The study will collect information on the changing biological, medical, psychological, social, and economic aspects of people's lives. These factors will be studied in order to understand how, individually and in combination, they have an impact in both maintaining health and in the development of disease and disability as people age. The CLSA will be one of the most comprehensive research platform of its kind undertaken to date, not only in Canada but around the world.
Drs. Parminder Raina (McMaster University), Christina Wolfson (McGill University), and Susan Kirkland (Dalhousie University), along with a team of more than 200 co-investigators and collaborators from 26 Canadian universities are working together to develop this innovative, multidisciplinary study.
Population ageing is at the centre of the policy debate in many countries. Populations projections show that 23% to 25% of the Canadian population will be aged 65 and over in 2031 and that the proportion of the oldest seniors (80 years and over) will also increase sharply. Since the large baby-boom generations are approaching retirement, many people will experience the transition from work to retirement. Aging will also affect labour force growth, old age income security expenditures, the health care system as well as the demand for informal care giving and home care services. Furthermore, a growing number of older Canadians will face the combined effects of a decline in physical function, medical problems and the development of chronic diseases.
For the first time, there will be the opportunity to begin to understand the complex interplay between physical, social and psychological determinants of health, including gene-gene and gene-environment interactions. This initiative will enable research to move beyond a snapshot of the adult Canadian population to observe and understand the disease, disability and psychosocial processes that accompany aging.
The overall aims of the CLSA are:
2001-2002: CIHR Institute of Aging issued a Request for Proposals (RFP) entitled: Protocol Design for the Canadian Longitudinal Study on Aging. The RFP was based on a CLSA Design Workshop held that same month in Aylmer, Quebec.
Launch and International Peer review of Request for Proposals, entitled: Protocol Design for the Canadian Longitudinal Study on Aging
Meritorious CLSA team (headed by 3 principal investigators (Dr. Parminder Raina, McMaster University, Dr. Christina Wolfson, McGill University, and Dr. Susan Kirkland, Dalhousie University) funded ($462,000) to develop CLSA Protocol Design
2002-2004: Development and International Peer review of CLSA Protocol Design
CLSA Team funded ($1,744,000) to support the CSLA Phase I: Methodological Feasibility Studies
2004-2006: Conduct of CLSA Phase I: Methodological Feasibility Studies
Development and International Peer review of CLSA Phase II Protocol
2006-2008: CLSA team funded ($2,100,000) to support the CLSA Phase II: Content Development and Validation
2008-2013: CLSA Team funded ($23.5 million) to support the CLSA Phase III: Initial Tracking and Comprehensive Cohorts. This 5-year implementation phase includes the first wave of recruitment and data collection on the initial tracking cohort and comprehensive cohort, follow-up on the initial tracking cohort, and management.
The Institute of Aging has launched a funding opportunity for CLSA Fellowships. The purpose of these fellowships is to build and strengthen research capacity and expertise in Canada in health measurement studies with emphasis on the CLSA and similar longitudinal studies of aging.
For more information, please visit the Canadian Longitudinal Study on Aging (CLSA) Fellowships webpage.
Health Canada, Statistics Canada, the Canadian Institute for Health Information, the Canadian Association on Gerontology, the Health Charities Council of Canada, Merck Frosst Canada and the other CIHR Institutes, as members of the CLSA Steering Committee between 2002 and 2006, joined in the planning and overseeing the study's protocol development. This approach was essential in making the CLSA relevant to various sectors.
The CLSA team is also working with CIHR and Canadian experts in fields such as ethics, law and sociology, to ensure that all research is done in an ethical manner, respecting the values of Canadian society and the rights of those involved in the study. As required in Canada, all research will also need to be approved and monitored by research ethics boards.
The CLSA team will develop partnerships with federal and provincial governments, health charities and the private sector to sustain the long-term vision of the CLSA.
Advisory Committee on Ethical, Legal, and Social Issues (ELSI) for the CLSA
In the summer of 2009 CIHR established a Advisory Committee on Ethical, Legal, and Social Issues (ELSI) for the CLSA. The committee's mandate is to advise the Scientific Management Team leading the CLSA on actions and best practices to address ethical, legal and social issues relevant to CLSA.
The National launch of the Canadian Longitudinal Study on Aging was on Thursday, May 21, 2009 at McMaster University in Hamilton. Please read the news release for more details.
For questions about this initiative contact:
Linda Mealing, PhD
Associate Director, CLSA
Canadian Institutes of Health Research
Telephone: 613-941-0057
Fax: 613-954-1800
Email: linda.mealing@cihr-irsc.gc.ca
For more information on the CLSA, please visit: Canadian Longitudinal Study on Aging.